{"id":"W4402893929","doi":"10.1093/ve/veae082","title":"Structural models predict a significantly higher binding affinity between the NblA protein of cyanophage Ma-LMM01 and the phycocyanin of <i>Microcystis aeruginosa</i> NIES-298 compared to the host homolog","year":2024,"lang":"en","type":"article","venue":"Virus Evolution","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"University of Waterloo; Natural Sciences and Engineering Research Council of Canada; Mitacs; Phycological Society of America","keywords":"Phycobilisome; Phycocyanin; Microcystis aeruginosa; Biology; Allophycocyanin; Cyanobacteria; Microcystis; Lytic cycle; Anabaena variabilis; Gene; Microbiology; Biochemistry; Virus; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001305759,0.0009713582,0.0005684076,0.0002358332,0.0005610764,0.0006298387,0.0005698305,0.0008549576,0.003508605],"category_scores_gemma":[0.0002776064,0.0002466709,0.0006569257,0.0001983468,0.0001874827,0.0003674468,0.0002375997,0.0006711931,0.0006003364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008536648,"about_ca_system_score_gemma":0.0006254552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006124833,"about_ca_topic_score_gemma":0.003885015,"domain_scores_codex":[0.9999154,0.00001744496,0.000004139437,0.00001692679,0.00002558476,0.00002044229],"domain_scores_gemma":[0.9998678,0.00003907559,0.00002817105,0.000008678914,0.00002307545,0.00003315786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001760352,0.001416908,0.03578833,0.0008567303,0.0005919173,0.002120732,0.0005082389,0.3629332,0.5711623,0.007983659,0.002794571,0.01208299],"study_design_scores_gemma":[0.0002058527,0.0006670404,0.02005201,0.00006951005,0.0001520864,0.0004804374,0.0004214852,0.9189428,0.05350731,0.001812468,0.003633843,0.00005513537],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887789,0.0004103262,0.007723921,0.0001746978,0.00002483878,0.0000331438,0.0003932597,0.0003030983,0.002157651],"genre_scores_gemma":[0.9939371,0.0002159708,0.003637156,0.00004295413,0.000005517989,0.00004207333,0.001188217,0.00005483976,0.0008760929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006124833,"threshold_uncertainty_score":0.01217836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01256182382256133,"score_gpt":0.22559907460514,"score_spread":0.2130372507825787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}