{"id":"W4402926981","doi":"10.1007/7651_2024_571","title":"Assessing Autophagy Flux in Glioblastoma Temozolomide Resistant Cells","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Temozolomide; Autophagy; Glioblastoma; Flux (metallurgy); Cancer research; Medicine; Chemistry; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002135969,0.0002490577,0.0004709453,0.000347553,0.0003107654,0.0003740978,0.0001824774,0.0002874062,0.00112896],"category_scores_gemma":[0.00008630677,0.0001244669,0.0002524877,0.0007109914,0.0001868634,0.0002584526,0.0001446774,0.0005440245,0.0002511269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000464142,"about_ca_system_score_gemma":0.0003118817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004895068,"about_ca_topic_score_gemma":0.004515336,"domain_scores_codex":[0.9997948,0.00002594035,0.00002745125,0.00003983088,0.00007159711,0.00004043836],"domain_scores_gemma":[0.9999346,0.00001200541,0.0000117658,0.000007577655,0.00002275938,0.00001127615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003465388,0.000091965,0.000745279,0.00006670496,0.00001766899,0.00006086312,0.0001061672,0.0001972815,0.9960551,0.0002612546,0.0001490036,0.001902154],"study_design_scores_gemma":[0.00002905204,0.0004180636,0.01464919,0.000007820145,0.00003907239,0.0001835706,0.0001702066,0.002784527,0.9790536,0.00009021527,0.002564844,0.000009781709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921085,0.0008872569,0.002531789,0.00008876213,0.00004816244,0.00003327333,0.00138424,0.00008217027,0.002835883],"genre_scores_gemma":[0.9863082,0.001304927,0.005258672,0.00008693004,0.00001200688,0.0001092672,0.001776941,0.00003454996,0.005108641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004895068,"threshold_uncertainty_score":0.00973314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02391043330207603,"score_gpt":0.4337185282828551,"score_spread":0.4098080949807791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}