{"id":"W4402933243","doi":"10.3389/frmbi.2024.1380152","title":"Effects of oral liquiritigenin inoculation on gut microbiota and gene expression in intestinal and extraintestinal tissues of mice","year":2024,"lang":"en","type":"article","venue":"Frontiers in Microbiomes","topic":"Pharmacological Effects of Natural Compounds","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Natural Science Foundation of China","keywords":"Liquiritigenin; Gene expression; Inoculation; Gut flora; Gene; Biology; Microbiology; Immunology; Medicine; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005226552,0.0002385211,0.0004067627,0.000568703,0.00003830589,0.00001743557,0.000167831,0.0002697942,0.00002650675],"category_scores_gemma":[0.0001561416,0.0002133676,0.00004999767,0.0003646272,0.0005080789,0.0001303392,0.000129942,0.0006425149,0.000001824726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008278391,"about_ca_system_score_gemma":0.00003409968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001871183,"about_ca_topic_score_gemma":0.000003878274,"domain_scores_codex":[0.998396,0.0004490669,0.0004011938,0.000388125,0.00007365296,0.00029199],"domain_scores_gemma":[0.9988888,0.0008209725,0.000099932,0.00007109566,0.00003890516,0.00008028502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005762135,0.000209502,0.01396502,0.000845398,0.000043444,0.0001373141,0.0004379114,0.00004202869,0.9645334,0.00002736005,0.003310242,0.01587217],"study_design_scores_gemma":[0.001722341,0.0004570747,0.03112406,0.0007592703,0.0000621118,0.00007436916,0.00004852691,0.002074626,0.9614889,0.0004422689,0.001529574,0.0002169024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773848,0.02072139,0.0002669633,0.0002253639,0.0007812264,0.0005079455,0.00002953344,0.00003586304,0.00004690784],"genre_scores_gemma":[0.9836458,0.0004933376,0.01555837,0.0001419167,0.00003398817,0.00001678907,0.00001977212,0.00001710289,0.00007295212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02022805,"threshold_uncertainty_score":0.8700877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03315199166357274,"score_gpt":0.380372735911044,"score_spread":0.3472207442474713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}