{"id":"W4402965469","doi":"10.4049/jimmunol.2400233","title":"Microbe-binding Antibodies in the Female Genital Tract: Associations with the Vaginal Microbiome and Genital Immunology","year":2024,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto","funders":"Medical Research Council; Canadian Institutes of Health Research; Foreign, Commonwealth and Development Office","keywords":"Bacterial vaginosis; Biology; Microbiology; Lactobacillus crispatus; Prevotella; Immunology; Gardnerella vaginalis; Proinflammatory cytokine; Microbiome; Immunoglobulin A; Lactobacillus; Bacteria; Immune system; Chemokine; Antibody; Inflammation; Immunoglobulin G","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003026986,0.0001992766,0.000188084,0.0007766504,0.0002168703,0.0004375448,0.0001603599,0.0004428369,0.001134995],"category_scores_gemma":[0.0006880531,0.0001330745,0.00008677261,0.0004229521,0.0003672571,0.0002265683,0.0001961705,0.000229123,0.0001202372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001883138,"about_ca_system_score_gemma":0.0001710291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001493176,"about_ca_topic_score_gemma":0.00198864,"domain_scores_codex":[0.999858,0.00004072415,0.000008677504,0.00002970188,0.00002878742,0.00003401695],"domain_scores_gemma":[0.9997657,0.00007099121,0.00008059369,0.00001569734,0.00003444428,0.00003262509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002748974,0.00009623054,0.86933,0.0001481802,0.00006258264,0.000254127,0.0003463621,0.00007554295,0.1079649,0.000108034,0.0001158725,0.02122326],"study_design_scores_gemma":[0.000003740156,0.0001618079,0.9943423,0.00001862823,0.00001803822,0.0005912149,0.0002032296,0.0001552205,0.00390707,0.00005656305,0.0005378034,0.000004287223],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996174,0.002873651,0.0002741808,0.00008226837,0.000005722299,0.00001123288,0.00008854933,0.000004971335,0.0004854952],"genre_scores_gemma":[0.9981828,0.0008748415,0.0005681258,0.0000434551,0.00001418762,0.000009107397,0.00005767041,0.000001542737,0.0002482481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001493176,"threshold_uncertainty_score":0.003796935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01744452628117271,"score_gpt":0.2840308964635141,"score_spread":0.2665863701823414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}