{"id":"W4402969557","doi":"10.7326/annals-24-02228-jc","title":"In ischemic stroke treated within 4.5 h, reteplase vs. alteplase increased excellent functional outcome at 90 d","year":2024,"lang":"en","type":"article","venue":"Annals of Internal Medicine","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Reteplase; Medicine; Ischemic stroke; Stroke (engine); Internal medicine; Tissue plasminogen activator; Fibrinolytic agent; Cardiology; Thrombolysis; Ischemia; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009049764,0.0004347409,0.001572742,0.0003552184,0.0002190814,0.0008395676,0.0003660525,0.000873287,0.007292901],"category_scores_gemma":[0.002643344,0.0001831882,0.001657912,0.0003431299,0.0002177522,0.0006178468,0.0003641954,0.001480239,0.0009470861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005279419,"about_ca_system_score_gemma":0.0008084934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002777167,"about_ca_topic_score_gemma":0.007399882,"domain_scores_codex":[0.999307,0.0003311505,0.00006382731,0.00008582402,0.00004392828,0.0001681789],"domain_scores_gemma":[0.999246,0.000374398,0.0001279762,0.00003701383,0.00002821999,0.0001863975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.813497,0.004818716,0.01725984,0.0009400726,0.004707288,0.0002615153,0.00008364473,0.0008937425,0.004337367,0.0003550681,0.01244262,0.1404031],"study_design_scores_gemma":[0.2303014,0.2336655,0.4912336,0.0009995825,0.0183225,0.0007473559,0.0004624013,0.004689377,0.00482255,0.002992531,0.01154161,0.0002216086],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662569,0.01418008,0.0004304011,0.002695347,0.001753546,0.0002167288,0.002401524,0.0001221345,0.0119434],"genre_scores_gemma":[0.9907669,0.003091725,0.0003592587,0.001093818,0.0006301136,0.000116213,0.001067902,0.00001149736,0.002862696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007292901,"threshold_uncertainty_score":0.02439719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04764295263374452,"score_gpt":0.3285563329019669,"score_spread":0.2809133802682224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}