{"id":"W4403005255","doi":"10.2174/0113892002331260240919055056","title":"Ceftobiprole and Cefiderocol for Patients on Extracorporeal Membrane Oxygenation: The Role of Therapeutic Drug Monitoring","year":2024,"lang":"en","type":"article","venue":"Current Drug Metabolism","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Toronto General Hospital; University of Toronto","funders":"","keywords":"Extracorporeal membrane oxygenation; Therapeutic drug monitoring; Medicine; Intensive care medicine; Antimicrobial; Pharmacokinetics; Antibiotics; Drug; Pharmacology; Extracorporeal; Internal medicine; Biology; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004421055,0.0003681044,0.0003690604,0.0004769044,0.0002754566,0.0009932176,0.0002798535,0.0007766197,0.001141266],"category_scores_gemma":[0.002031279,0.00009100628,0.0001945471,0.0003383642,0.0005028833,0.0007874235,0.000348091,0.001020181,0.0002265635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004182892,"about_ca_system_score_gemma":0.0007669141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000693128,"about_ca_topic_score_gemma":0.0007925116,"domain_scores_codex":[0.9996812,0.0001233381,0.00004960039,0.00003709916,0.0000677787,0.00004098764],"domain_scores_gemma":[0.9992494,0.0002861749,0.0002569342,0.00003087999,0.00005870704,0.0001178938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001422284,0.000200778,0.283353,0.0006932644,0.00009228988,0.1010908,0.0008448496,0.001038752,0.01613059,0.003132961,0.006012138,0.5859883],"study_design_scores_gemma":[0.0001373888,0.001736864,0.263045,0.002082688,0.0002642817,0.5981121,0.002217273,0.008838975,0.02473413,0.0066447,0.09207454,0.0001119914],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7619473,0.1569928,0.01310316,0.03284313,0.0004826417,0.000087377,0.000125236,0.0002014623,0.03421693],"genre_scores_gemma":[0.9789193,0.01555608,0.003046885,0.001229779,0.0004768203,0.00001193306,0.00005441059,0.00001578746,0.0006890082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001141266,"threshold_uncertainty_score":0.003817976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01882659499917749,"score_gpt":0.3091703931537338,"score_spread":0.2903437981545564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}