{"id":"W4403053730","doi":"10.1200/jco.2022.40.16_suppl.6006","title":"Association of plasma tumor tissue modified viral HPV DNA (TTMV) with tumor burden, treatment type, and outcome: A translational analysis from NRG-HN002.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cancer Care Ontario; McGill University; University of Calgary","funders":"National Institutes of Health","keywords":"Medicine; Oncology; Cancer research; DNA; Internal medicine; Virology; Pathology; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007000655,0.0007817117,0.0007438319,0.0004156431,0.0003758762,0.0004378125,0.0008337196,0.0004734184,0.003662891],"category_scores_gemma":[0.002379753,0.0002911113,0.001463838,0.000673348,0.001148992,0.0004462422,0.000626119,0.001110373,0.0005923728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001008559,"about_ca_system_score_gemma":0.001819851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002026576,"about_ca_topic_score_gemma":0.003150833,"domain_scores_codex":[0.9986385,0.0008301625,0.00004442101,0.0001849872,0.0001774082,0.0001245923],"domain_scores_gemma":[0.9979272,0.000497127,0.0005031643,0.0005708192,0.0001418102,0.0003598162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.599646,0.01974782,0.2354255,0.0008505911,0.004210331,0.0003817372,0.0006480303,0.001592874,0.0653291,0.0004637508,0.004316048,0.06738825],"study_design_scores_gemma":[0.03086013,0.2109113,0.7415761,0.00007809377,0.002181521,0.0006931038,0.0003098831,0.001800677,0.006160455,0.0005189466,0.00485462,0.00005509222],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956756,0.0006013869,0.0008622504,0.0001997391,0.00002357942,0.0003717717,0.001481001,0.0000228753,0.0007617901],"genre_scores_gemma":[0.9919418,0.0002587369,0.001154921,0.0002926362,0.00005835268,0.0004408497,0.004554156,0.00002347581,0.001275134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007000655,"threshold_uncertainty_score":0.03702343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04006275547846992,"score_gpt":0.3712870080761294,"score_spread":0.3312242525976595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}