{"id":"W4403057996","doi":"10.1055/s-0044-1789696","title":"Guselkumab and golimumab combination induction therapy in ulcerative colitis results in early local tissue healing that is sustained through guselkumab maintenance therapy","year":2024,"lang":"en","type":"article","venue":"Zeitschrift für Gastroenterologie","topic":"Liver physiology and pathology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Golimumab; Ulcerative colitis; Medicine; Maintenance therapy; Surgery; Internal medicine; Chemotherapy; Tumor necrosis factor alpha; Infliximab; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003138324,0.0002351484,0.0007523068,0.0002650238,0.0001672343,0.0003065016,0.0001751532,0.000316139,0.001225272],"category_scores_gemma":[0.0002361092,0.0001056675,0.0004671107,0.0002111666,0.0002337027,0.0002249316,0.0001707142,0.001040638,0.000389062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002684486,"about_ca_system_score_gemma":0.0002280183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002277591,"about_ca_topic_score_gemma":0.0006268307,"domain_scores_codex":[0.9998674,0.00003872518,0.00001277904,0.00001184756,0.00001955027,0.00004960991],"domain_scores_gemma":[0.9998893,0.00002385732,0.00002624866,0.00001104037,0.000005893276,0.00004373353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1293506,0.004414339,0.008841658,0.001200522,0.0006672379,0.003012519,0.0001419444,0.001177661,0.2993184,0.0006097251,0.004707389,0.546558],"study_design_scores_gemma":[0.0519536,0.2132354,0.4325248,0.0004809975,0.003084995,0.02188949,0.0004231785,0.007339458,0.2145521,0.001163204,0.05319777,0.0001549505],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854155,0.01167635,0.0004706137,0.0004359725,0.0001185934,0.00004784916,0.00008294974,0.000102305,0.001649768],"genre_scores_gemma":[0.9962537,0.00179864,0.0007303286,0.0001693067,0.00006212554,0.00003984833,0.0001442835,0.000009800267,0.000792084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001225272,"threshold_uncertainty_score":0.004098892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03682470314107087,"score_gpt":0.3207667184244885,"score_spread":0.2839420152834176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}