{"id":"W4403069181","doi":"10.1099/acmi.0.000925.v1","title":"Immunogenicity of virus-like particle vaccine candidates against SARS-CoV-2 infection","year":2024,"lang":"en","type":"preprint","venue":"","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Immunogenicity; Virology; Coronavirus disease 2019 (COVID-19); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virus-like particle; 2019-20 coronavirus outbreak; Virus; Medicine; Biology; Immunology; Antigen; Outbreak; Infectious disease (medical specialty); Disease; Recombinant DNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002499891,0.0002735088,0.000253921,0.0001642706,0.00008369964,0.0003128764,0.0001643871,0.0003736592,0.0009836063],"category_scores_gemma":[0.0002897048,0.00008587191,0.0002077745,0.00009628413,0.0001153489,0.0002178257,0.0001658064,0.0004244197,0.000292637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001668625,"about_ca_system_score_gemma":0.0001278507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000205334,"about_ca_topic_score_gemma":0.0001648611,"domain_scores_codex":[0.9998971,0.00002376658,0.000006969107,0.00001590183,0.00002437794,0.0000318703],"domain_scores_gemma":[0.9999193,0.00001716615,0.00001574939,0.000008193133,0.00001659117,0.00002298382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002609493,0.0001042649,0.0005914088,0.00003246651,0.00001094995,0.00004418398,0.00001701772,0.0003633816,0.9966192,0.00006970991,0.00005396081,0.001832585],"study_design_scores_gemma":[0.0001319304,0.006663422,0.01157819,0.00001907344,0.00005573048,0.0004661519,0.00006310847,0.003146895,0.9743543,0.0001549506,0.003355681,0.00001053051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981584,0.0003672449,0.0008316395,0.00004139017,0.00001692551,0.00002428955,0.0000769809,0.0000135002,0.0004696015],"genre_scores_gemma":[0.9974286,0.0002128955,0.0009115916,0.0000515166,0.00001426889,0.0000208786,0.0005080773,0.000006983725,0.0008451795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009836063,"threshold_uncertainty_score":0.003290474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0443890539789701,"score_gpt":0.3606607411984799,"score_spread":0.3162716872195098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}