{"id":"W4403072309","doi":"10.1093/clinchem/hvae106.584","title":"B-224 Rapid, Extraction-Free, and Portable Molecular Detection of HIV-1 and HCV Directly From Whole Blood","year":2024,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"","keywords":"Human immunodeficiency virus (HIV); Extraction (chemistry); Whole blood; Virology; Medicine; Chromatography; Chemistry; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001207436,0.0001138205,0.0001464555,0.00000896408,0.0000387727,0.00002332159,0.00008337585,0.0002359832,0.000008703463],"category_scores_gemma":[0.0001518705,0.000112466,0.00007523914,0.00005903886,0.0001643562,0.000004957548,0.0001131107,0.0001612361,0.000001173357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003285661,"about_ca_system_score_gemma":0.00002508334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007493676,"about_ca_topic_score_gemma":0.000001892398,"domain_scores_codex":[0.9991134,0.00001420941,0.0002854533,0.0004189595,0.00006257775,0.0001054295],"domain_scores_gemma":[0.9993815,0.00005535041,0.00007181041,0.0003696939,0.00004059867,0.00008098196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001735191,0.00005038983,0.0003533788,0.00004117611,0.00004689167,0.000005555422,0.000002029536,5.576065e-7,0.9869004,0.00001126678,0.0005794975,0.01199146],"study_design_scores_gemma":[0.000219533,0.00005271896,0.0003054435,0.00003851483,0.00007199783,0.00002034453,0.00001284498,0.0001043012,0.9406748,0.0009249338,0.0574518,0.0001227612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889234,0.004805881,0.004993067,0.0002919257,0.00004590523,0.00008049511,0.0001073717,0.00005450402,0.0006974493],"genre_scores_gemma":[0.9928225,0.001120326,0.005117712,0.00006620806,0.0001955749,0.00001174221,0.0001268764,0.0000197267,0.0005193363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0568723,"threshold_uncertainty_score":0.458623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082990644525632,"score_gpt":0.3104584734532227,"score_spread":0.2996285670079664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}