{"id":"W4403074535","doi":"10.1242/jcs.262298","title":"<i>prominin-1</i> -null <i>Xenopus laevis</i> develop subretinal drusenoid-like deposits, cone-rod dystrophy and RPE atrophy","year":2024,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Alberta","funders":"National Eye Institute; BrightFocus Foundation; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC; University of Alberta","keywords":"Biology; Xenopus; Retina; Retinal degeneration; Retinal; Retinal pigment epithelium; Atrophy; Anatomy; Pathology; Neuroscience; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006542637,0.0001929283,0.0001966739,0.000149013,0.0001891329,0.0002609993,0.0004269889,0.00008216824,0.00001606072],"category_scores_gemma":[0.00006936175,0.0001536588,0.00008185044,0.0005022069,0.0004297396,0.00004046396,0.0001664032,0.0001938421,0.00001172025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000290379,"about_ca_system_score_gemma":0.0008029073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003921162,"about_ca_topic_score_gemma":0.000004052513,"domain_scores_codex":[0.9983436,0.00003745267,0.0004084108,0.0003674102,0.0004798,0.0003633065],"domain_scores_gemma":[0.9991316,0.00002320734,0.0001725771,0.0001517261,0.0002818769,0.0002390198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001082246,0.00003000175,0.001662457,0.00005353699,0.00001727296,0.00009103274,0.0001243449,0.000006823135,0.9916456,0.00006697935,0.004479546,0.001714134],"study_design_scores_gemma":[0.0006703518,0.0008002679,0.003883424,0.0001007715,0.00005375082,0.0007295679,0.0001769969,0.00004668064,0.8648649,0.0001294727,0.1281687,0.000375055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988332,0.005740611,0.0006361058,0.0003812002,0.0007175885,0.00008713132,0.000003026072,0.000007985586,0.004094341],"genre_scores_gemma":[0.9918532,0.001292941,0.00559698,0.0003289493,0.0001937292,0.000001732773,0.000004979954,0.00001676647,0.0007107301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1267807,"threshold_uncertainty_score":0.6266022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004439271819626381,"score_gpt":0.2185362364304694,"score_spread":0.214096964610843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}