{"id":"W4403079162","doi":"10.1101/2024.09.30.24314665","title":"Risk of Incident Cytopenia in Clonal Hematopoiesis","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Hematological disorders and diagnostics","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institutes of Health; Edward P. Evans Foundation; Alexander and Margaret Stewart Trust","keywords":"Cytopenia; Haematopoiesis; Medicine; Biology; Genetics; Immunology; Bone marrow; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006949814,0.0002084047,0.0001997819,0.0006228666,0.0002565151,0.0006598384,0.000348402,0.0003913665,0.002767541],"category_scores_gemma":[0.002482884,0.0002282906,0.0002523881,0.000636455,0.000256367,0.0002600964,0.0003878688,0.0005784433,0.0002099183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001961363,"about_ca_system_score_gemma":0.0001982148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003323991,"about_ca_topic_score_gemma":0.002617227,"domain_scores_codex":[0.9995294,0.0001294805,0.0000310116,0.0001674739,0.00007596892,0.00006665212],"domain_scores_gemma":[0.9981202,0.0004035667,0.0009052292,0.0001564383,0.0001558265,0.0002586449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001407211,0.00001114466,0.9984674,0.000004511486,0.00002750678,0.00004709458,0.00001092432,0.00005956891,0.0002491405,0.00002492364,0.0001095111,0.0008474774],"study_design_scores_gemma":[0.000007607698,0.0000796651,0.9981158,0.000007586846,0.00003720786,0.0004971501,0.00003910227,0.0007306651,0.000226217,0.00008759517,0.0001674187,0.000003915845],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986669,0.0002932388,0.0001562043,0.00003563431,0.000005670445,0.000004958506,0.0004535441,0.00001294282,0.0003708047],"genre_scores_gemma":[0.9995562,0.0000330041,0.00005364958,0.00001117561,0.000005518975,0.000002234534,0.0002132909,0.000001908033,0.0001229686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003323991,"threshold_uncertainty_score":0.00925833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02149540129551986,"score_gpt":0.3011514292196111,"score_spread":0.2796560279240913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}