{"id":"W4403082926","doi":"10.1111/all.16303","title":"Interleukin‐5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils","year":2024,"lang":"en","type":"review","venue":"Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Sanofi Genzyme; Fonds De La Recherche Scientifique - FNRS; Department of Health and Social Care; Celltrion; Sanofi; Teva Pharmaceutical Industries; National Institute for Health and Care Research; Regeneron Pharmaceuticals; Genentech; AstraZeneca; GlaxoSmithKline; Amgen","keywords":"Immunology; Eosinophil; Innate lymphoid cell; Cytokine; Inflammation; Allergic inflammation; Interleukin 33; Interleukin 5; Biology; Interleukin; Medicine; Innate immune system; Immune system; Asthma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007339175,0.0004752026,0.001147726,0.0002486914,0.00006836864,0.00006591724,0.0001077024,0.0003126294,0.0001137624],"category_scores_gemma":[0.0001762582,0.0003176336,0.0002747687,0.0002831696,0.00006702683,0.00004782356,0.00009476745,0.0004967971,0.0005190836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009734373,"about_ca_system_score_gemma":0.0004830391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005540631,"about_ca_topic_score_gemma":0.000005464362,"domain_scores_codex":[0.998407,0.0001125338,0.0004643911,0.0004961453,0.0002676903,0.0002522609],"domain_scores_gemma":[0.9989928,0.0001947227,0.0001590324,0.0003606481,0.00005573599,0.0002370473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003582217,0.00003275639,0.000001769732,0.02486409,0.0004407014,0.0008650722,0.00006406756,2.742963e-7,0.0000186474,0.0008595214,0.002337593,0.9704797],"study_design_scores_gemma":[0.0003253365,0.001276349,0.00002254742,0.02531761,0.0008928567,0.0002015556,0.00001185584,0.000004367013,0.00003497496,0.00007221065,0.9715697,0.0002706127],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001566331,0.9906048,0.000001340645,0.0001912696,0.0004672295,0.0006809412,0.00001093225,0.0001167152,0.006360464],"genre_scores_gemma":[0.000782407,0.9947184,0.00004906761,0.0003539319,0.001827181,0.00008909118,0.0001798289,0.00009535968,0.001904687],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9702091,"threshold_uncertainty_score":0.9999276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02179278863359118,"score_gpt":0.3215775768362434,"score_spread":0.2997847882026523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}