{"id":"W4403118269","doi":"10.1101/2024.10.04.616615","title":"Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Open Philanthropy Project; Novo Nordisk; Innovationsfonden","keywords":"Virology; Glycoprotein; Envelope (radar); Antibody; Hepatitis C virus; Viral envelope; Virus; Chemistry; Biology; Immunology; Computer science; Molecular biology; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004231195,0.001138705,0.0002203035,0.0003234932,0.0001171853,0.0002380759,0.0004307461,0.0004468616,0.001447011],"category_scores_gemma":[0.0002110621,0.0002093738,0.0002958649,0.0002162676,0.0002121753,0.0002717908,0.0004582939,0.0006413966,0.0004597685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003574419,"about_ca_system_score_gemma":0.0001307475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004546114,"about_ca_topic_score_gemma":0.0005358508,"domain_scores_codex":[0.9995894,0.00009292633,0.00003714553,0.00008917125,0.00009675774,0.00009455621],"domain_scores_gemma":[0.9998721,0.00002807176,0.00003509499,0.00001387382,0.00002227682,0.00002861874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007902354,0.00006317502,0.0001698055,0.00003901405,0.00001326995,0.00001519133,0.000006947366,0.0001929322,0.9976318,0.0001037319,0.00004260058,0.001642525],"study_design_scores_gemma":[0.00002608112,0.0005582445,0.001253191,0.000008140601,0.00003366148,0.0001126559,0.00000758674,0.001023036,0.9950947,0.00003007398,0.001847089,0.000005588246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851105,0.001379345,0.01086038,0.00006668896,0.00004766754,0.00008028421,0.0001692442,0.0001133111,0.002172501],"genre_scores_gemma":[0.9893247,0.0007954455,0.007290917,0.0001723768,0.00001728609,0.00007623023,0.0004441963,0.00002771153,0.001850959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001447011,"threshold_uncertainty_score":0.004840791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02322046692074837,"score_gpt":0.2641641390047327,"score_spread":0.2409436720839843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}