{"id":"W4403118650","doi":"10.1038/s41467-024-52974-3","title":"Astrocytic neuroligin 3 regulates social memory and synaptic plasticity through adenosine signaling in male mice","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Canada Research Chairs; University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China; Government of Canada","keywords":"Neuroligin; Synaptic plasticity; Neuroscience; Adenosine; Synapse; Biology; Neuroplasticity; Metaplasticity; Signal transduction; Cell biology; Excitatory postsynaptic potential; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002061813,0.0008215855,0.0003910431,0.001112877,0.0003876313,0.0004078491,0.0005462812,0.0008119916,0.002162396],"category_scores_gemma":[0.000109968,0.0003863701,0.0007308167,0.0002392663,0.0006859733,0.0003449796,0.0003568296,0.001193725,0.0008061159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006842734,"about_ca_system_score_gemma":0.0004282568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002133463,"about_ca_topic_score_gemma":0.004993262,"domain_scores_codex":[0.9997123,0.00003249585,0.00002842188,0.00006776852,0.00008262461,0.0000765308],"domain_scores_gemma":[0.9997219,0.00001575914,0.000125808,0.00002022428,0.00001874279,0.00009753467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003804999,0.00008678185,0.0003854702,0.00003598862,0.0000158761,0.0002430139,0.00004088707,0.0000637974,0.9971542,0.0002484857,0.00009744396,0.001247407],"study_design_scores_gemma":[0.0001619674,0.0009583363,0.01963557,0.00003225626,0.0001029725,0.0009276984,0.0002067469,0.00150576,0.9726376,0.0003993939,0.003408192,0.00002353729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890295,0.001305589,0.00434566,0.0006017784,0.00009206485,0.00005373276,0.001522473,0.0004300066,0.002619228],"genre_scores_gemma":[0.9844162,0.001177061,0.003116026,0.0002449469,0.00003132287,0.0001534177,0.000962017,0.0001609528,0.009738105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002162396,"threshold_uncertainty_score":0.007233918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02958828167547803,"score_gpt":0.297840097892634,"score_spread":0.268251816217156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}