{"id":"W4403130863","doi":"10.1002/acr2.11732","title":"Persistent Patient‐Level Effect of Guselkumab at Consecutive 8‐Week Dosing Visits and Over Time in Patients With Active Psoriatic Arthritis: Post Hoc Analysis of a 2‐Year, Phase 3, Randomized, Controlled Study","year":2024,"lang":"en","type":"article","venue":"ACR Open Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Arthritis Society; University of Toronto; McGill University; University Health Network","funders":"Janssen Research and Development; Yale University","keywords":"Medicine; Psoriatic arthritis; Dosing; Randomized controlled trial; Post-hoc analysis; Clinical trial; Physical therapy; Internal medicine; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00762033,0.0013618,0.003331717,0.0004276068,0.0004868418,0.001333528,0.0007263273,0.001231689,0.00301283],"category_scores_gemma":[0.004193551,0.0005113186,0.00391925,0.0005526101,0.001066572,0.001220818,0.0004667417,0.002592284,0.0005270249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007302211,"about_ca_system_score_gemma":0.001585523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005101879,"about_ca_topic_score_gemma":0.001176555,"domain_scores_codex":[0.9967931,0.001822746,0.0002833517,0.0004657758,0.000276372,0.000358536],"domain_scores_gemma":[0.9955755,0.001570439,0.001308132,0.0006752625,0.0002963606,0.0005742523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9651699,0.008325557,0.004876982,0.0002737023,0.003134235,0.00003472789,0.00008847592,0.0005402187,0.004534644,0.00005166654,0.0003400919,0.01262986],"study_design_scores_gemma":[0.5027969,0.4372383,0.04925301,0.00003160412,0.004773819,0.00008100676,0.00006805774,0.001560732,0.003057144,0.0002128589,0.0008675008,0.00005903696],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972288,0.0008442768,0.0003522008,0.00008695154,0.00006881517,0.0005135726,0.0003975634,0.00003891025,0.0004688687],"genre_scores_gemma":[0.9968951,0.0002935054,0.0006344096,0.000155717,0.0001228687,0.0008945765,0.0004493046,0.00001326521,0.0005413509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00762033,"threshold_uncertainty_score":0.04030067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006811951600269144,"score_gpt":0.2727698745731734,"score_spread":0.2659579229729042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}