{"id":"W4403130863","doi":"10.1002/acr2.11732","title":"Persistent Patient‐Level Effect of Guselkumab at Consecutive 8‐Week Dosing Visits and Over Time in Patients With Active Psoriatic Arthritis: Post Hoc Analysis of a 2‐Year, Phase 3, Randomized, Controlled Study","year":2024,"lang":"en","type":"article","venue":"ACR Open Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Arthritis Society; University of Toronto; McGill University; University Health Network","funders":"Janssen Research and Development; Yale University","keywords":"Medicine; Psoriatic arthritis; Dosing; Randomized controlled trial; Post-hoc analysis; Clinical trial; Physical therapy; Internal medicine; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004227757,0.0003153104,0.004152058,0.000519282,0.00008074383,0.00002785315,0.00008912382,0.00008560457,0.0001922272],"category_scores_gemma":[0.0003592639,0.0002069479,0.0003650348,0.0005468326,0.0002384002,0.0001273597,0.0002252422,0.0001203641,0.00000721649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001230515,"about_ca_system_score_gemma":0.00007472873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009647035,"about_ca_topic_score_gemma":0.000653802,"domain_scores_codex":[0.99742,0.0006501582,0.0008372639,0.0005000565,0.000311428,0.0002811181],"domain_scores_gemma":[0.9973778,0.001718329,0.000372472,0.0002513549,0.0001942489,0.00008581136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7432082,0.003060425,0.1905455,0.0001381696,0.04104085,0.0002393423,0.01298604,0.000004093006,0.00001719031,0.00002582731,0.00002946682,0.00870491],"study_design_scores_gemma":[0.9066699,0.02175848,0.05703325,0.001049055,0.01031721,0.00004205551,0.002386838,0.0004465749,0.0000838032,0.000004169406,0.000003445647,0.0002052648],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892138,0.003867685,0.000001825368,0.00004074003,0.00008097637,0.0063691,0.0002980685,0.00001252853,0.0001152426],"genre_scores_gemma":[0.9990914,0.0002761728,0.00004112324,0.00001988269,0.000001412945,0.0003785286,0.0001348701,0.00002459482,0.0000320188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1634617,"threshold_uncertainty_score":0.8439089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006811951600269144,"score_gpt":0.2727698745731734,"score_spread":0.2659579229729042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}