{"id":"W4403144430","doi":"10.1016/j.cellsig.2024.111447","title":"The major vault protein integrates adhesion-driven signals to regulate collagen remodeling","year":2024,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Arthritis Research Centre of Canada; University of Toronto","funders":"Institute of Musculoskeletal Health and Arthritis; Canada Foundation for Innovation","keywords":"Cell biology; Tissue remodeling; Adhesion; Chemistry; Biology; Inflammation; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001739026,0.000606885,0.0002403148,0.0002992598,0.0002659472,0.0004574812,0.0002297723,0.0004150655,0.001926229],"category_scores_gemma":[0.0001162201,0.0001853446,0.0004320646,0.0001416196,0.0001888823,0.000255066,0.0003579586,0.0004811745,0.0008497325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006666966,"about_ca_system_score_gemma":0.0001304073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000284595,"about_ca_topic_score_gemma":0.0004465754,"domain_scores_codex":[0.9997677,0.00004461942,0.00001476643,0.00005729105,0.00005549102,0.00006005161],"domain_scores_gemma":[0.9998667,0.00001378884,0.00004839615,0.00001428106,0.00001404269,0.00004278071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006232096,0.00001376893,0.0003503442,0.00003277242,0.000006206618,0.0001353656,0.00001041369,0.00005063219,0.9975032,0.0002180019,0.00008297381,0.001533955],"study_design_scores_gemma":[0.00001849988,0.0002275877,0.0143524,0.0000102317,0.00001852275,0.001310788,0.00004432249,0.002050055,0.9757672,0.0001277391,0.006061421,0.00001132033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986857,0.004182558,0.006071262,0.0002662964,0.00007833789,0.00003046505,0.0004110598,0.0001697081,0.001933296],"genre_scores_gemma":[0.9905624,0.0008000284,0.002954033,0.00009602598,0.00002168808,0.0000230658,0.0006648623,0.00002805865,0.004849833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001926229,"threshold_uncertainty_score":0.006443918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02631942858481475,"score_gpt":0.2940937663606421,"score_spread":0.2677743377758274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}