{"id":"W4403174123","doi":"10.1093/biolre/ioae140","title":"Development of <i>KISS1</i> knockout pigs is characterized by hypogonadotropic hypogonadism, normal growth, and reduced skatole","year":2024,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hendrix Genetics (Canada)","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Androstenone; Kisspeptin; Endocrinology; Biology; Skatole; Internal medicine; Ovulation; Adipose tissue; Gonadotropin; Testosterone (patch); Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004246395,0.0002286905,0.0006015572,0.0002372583,0.00005909973,0.000007643462,0.00008444794,0.0001726613,0.00004789498],"category_scores_gemma":[0.0001777791,0.0001997077,0.000101813,0.0002197716,0.0003217768,0.0001346236,0.00006626071,0.0001956936,0.00001569336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004892183,"about_ca_system_score_gemma":0.0002151985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002921163,"about_ca_topic_score_gemma":9.68518e-7,"domain_scores_codex":[0.9979526,0.00006379765,0.000633958,0.0009296166,0.0001642691,0.0002557467],"domain_scores_gemma":[0.9990039,0.00004184282,0.0002047367,0.0004757118,0.0001893398,0.00008446718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002524737,0.00009457785,0.00194385,0.0003666332,0.0002304567,0.000002812455,0.0006055079,1.934424e-8,0.8440959,0.000112359,0.0003930006,0.1519025],"study_design_scores_gemma":[0.0008692576,0.0003028111,0.03952351,0.00009529847,0.0001261668,0.0002676654,0.0001004102,0.000005786709,0.8478557,0.0001548491,0.1105122,0.0001862384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701337,0.02495898,0.0003022038,0.003096465,0.0005750153,0.0005706836,0.00002981679,0.00009433889,0.0002387928],"genre_scores_gemma":[0.9930166,0.0007779221,0.004581763,0.0000432945,0.0004251135,0.00005545915,0.00009278428,0.00003014548,0.000976907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1517162,"threshold_uncertainty_score":0.8143843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379887681112556,"score_gpt":0.2529885161450908,"score_spread":0.2391896393339652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}