{"id":"W4403186396","doi":"10.1021/acs.accounts.4c00196","title":"From Catalysis of Evolution to Evolution of Catalysis","year":2024,"lang":"en","type":"article","venue":"Accounts of Chemical Research","topic":"Origins and Evolution of Life","field":"Physics and Astronomy","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Nuclear Safety and Security Commission; Minerva Foundation","keywords":"Catalysis; Chemistry; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000559283,0.0001049433,0.0003073466,0.000362609,0.00002905696,0.00001911411,0.0003567783,0.00007168359,0.0005602472],"category_scores_gemma":[0.0001152569,0.0000971513,0.000191991,0.001228818,0.0001859142,0.0001997604,0.0001898337,0.0002211362,0.00008375489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002080172,"about_ca_system_score_gemma":0.0002847185,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01662338,"about_ca_topic_score_gemma":0.0000109462,"domain_scores_codex":[0.9981486,0.00004037227,0.000445616,0.0003050443,0.000777807,0.0002825479],"domain_scores_gemma":[0.9985535,0.0002776042,0.00007368361,0.000418202,0.00056571,0.0001113646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008376751,0.0003020612,0.01509362,0.0001499932,0.0003019164,4.573308e-7,0.0003671777,0.00003473035,0.9498955,0.02058864,0.008685239,0.004496883],"study_design_scores_gemma":[0.0003024663,0.00008062866,0.003585019,0.0003339587,0.0001108457,1.474488e-7,0.0009659905,0.001437036,0.9666923,0.02100693,0.005295409,0.0001892503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942234,0.0004807544,0.002078242,0.0002919313,0.00007422492,0.00009324497,0.000374903,0.00001147231,0.002371894],"genre_scores_gemma":[0.9989502,0.000003125616,0.0003336862,0.000001549036,0.0003260823,0.00001748094,0.0001091129,0.00001368961,0.0002450856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0167968,"threshold_uncertainty_score":0.989925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02546004963199895,"score_gpt":0.3669501532442475,"score_spread":0.3414901036122486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}