{"id":"W4403189935","doi":"10.1021/jasms.4c00320","title":"Mobile Phase Contaminants Affect Neutral Lipid Analysis in LC-MS-Based Lipidomics Studies","year":2024,"lang":"en","type":"article","venue":"Journal of the American Society for Mass Spectrometry","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario; Canada Foundation for Innovation; Ontario Research Foundation; Carleton University","keywords":"Lipidomics; Chemistry; Chromatography; Contamination; Lipidome; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004301158,0.001624536,0.0006592689,0.0008558917,0.0007393774,0.001680941,0.0007589029,0.001397116,0.001192247],"category_scores_gemma":[0.005800417,0.0006738109,0.0005213266,0.0008762246,0.001066498,0.001047033,0.001573537,0.00102601,0.001630112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005990604,"about_ca_system_score_gemma":0.001156149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001446175,"about_ca_topic_score_gemma":0.002984426,"domain_scores_codex":[0.9948624,0.00156154,0.0004310038,0.0008611358,0.001803403,0.0004806093],"domain_scores_gemma":[0.9971009,0.001382235,0.000398386,0.0001923535,0.0007923146,0.000133778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002440767,0.0000507619,0.002167001,0.0002047059,0.00004403929,0.0001679072,0.00008998668,0.0001458317,0.9915431,0.0001242027,0.0001397836,0.005078566],"study_design_scores_gemma":[0.00001615079,0.0002271805,0.006002996,0.00006246946,0.00007727821,0.0003454021,0.0001041595,0.001728982,0.9858223,0.0003176027,0.005267329,0.00002825909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7800181,0.02953049,0.174417,0.001650024,0.001145481,0.001475021,0.002016722,0.001585251,0.008161891],"genre_scores_gemma":[0.78443,0.0190929,0.1826548,0.002959867,0.0002705564,0.00123541,0.002866969,0.000839188,0.005650389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004301158,"threshold_uncertainty_score":0.02274698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01532386516013554,"score_gpt":0.3334739563281114,"score_spread":0.3181500911679758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}