{"id":"W4403190877","doi":"10.1080/2162402x.2024.2413719","title":"Benzodiazepines compromise the outcome of cancer immunotherapy","year":2024,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"HORIZON EUROPE European Research Council; Agence Nationale de la Recherche; HORIZON EUROPE Framework Programme; Cancéropôle Ile de France; Institut National Du Cancer; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Labex Immuno-Oncology; Association pour la Recherche sur le Cancer; Seerave Foundation; European Commission","keywords":"Medicine; Cancer immunotherapy; Immunotherapy; Compromise; Cancer; Internal medicine; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009581073,0.0001183715,0.0001894687,0.00007696782,0.00006737951,0.00002838626,0.0004327772,0.00007057838,0.0004241499],"category_scores_gemma":[0.00007755335,0.00007373468,0.0001074537,0.0002925991,0.0004294341,0.00006739989,0.00006281583,0.0002012984,0.00008448564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002460592,"about_ca_system_score_gemma":0.00004785786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002378734,"about_ca_topic_score_gemma":0.00004754053,"domain_scores_codex":[0.9990906,0.0001046398,0.0002448357,0.000240388,0.0001035788,0.0002160159],"domain_scores_gemma":[0.9992418,0.0003631386,0.00005559111,0.0003130744,0.00001370307,0.00001274471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005825363,0.00006243464,0.001186777,0.00003597316,0.00003720272,0.00001168796,0.000807118,0.00002071343,0.9050584,0.02028224,0.0009911574,0.07144801],"study_design_scores_gemma":[0.00126953,0.0002552437,0.04592364,0.00008471913,0.0000205078,0.00004684587,0.0003634381,0.0007018383,0.3818979,0.005289689,0.5637894,0.0003573313],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9694555,0.01903647,0.00006290532,0.006321738,0.001633859,0.0002365739,0.00002558309,0.0002849512,0.002942465],"genre_scores_gemma":[0.9958699,0.00140343,0.0000270647,0.001137514,0.00004831356,0.00004699648,8.33909e-7,0.00002977394,0.001436113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5627982,"threshold_uncertainty_score":0.4644143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0428168807187136,"score_gpt":0.3414093015550079,"score_spread":0.2985924208362943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}