{"id":"W4403190877","doi":"10.1080/2162402x.2024.2413719","title":"Benzodiazepines compromise the outcome of cancer immunotherapy","year":2024,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"HORIZON EUROPE European Research Council; Agence Nationale de la Recherche; HORIZON EUROPE Framework Programme; Cancéropôle Ile de France; Institut National Du Cancer; Institut Universitaire de France; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Labex Immuno-Oncology; Association pour la Recherche sur le Cancer; Seerave Foundation; European Commission","keywords":"Medicine; Cancer immunotherapy; Immunotherapy; Compromise; Cancer; Internal medicine; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001505747,0.0001129184,0.0002033413,0.00007850973,0.00009803777,0.0001470541,0.00008940406,0.0001511576,0.001121173],"category_scores_gemma":[0.0003344281,0.00002709221,0.00006874163,0.00005692761,0.00009390014,0.0001261235,0.000135249,0.0002979613,0.0002409728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001346725,"about_ca_system_score_gemma":0.0001555392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001534918,"about_ca_topic_score_gemma":0.0002812186,"domain_scores_codex":[0.9999223,0.00002234356,0.000006654539,0.000007077062,0.00001516693,0.00002644726],"domain_scores_gemma":[0.9998616,0.00002929034,0.00003611842,0.00001589572,0.00001935342,0.00003774652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.007135217,0.001669514,0.0218104,0.0004497758,0.0001574084,0.00114853,0.0002207557,0.0006655496,0.7547066,0.001279616,0.001399117,0.2093575],"study_design_scores_gemma":[0.001005714,0.05907401,0.270029,0.0001533708,0.0004986833,0.01155103,0.0006324535,0.003804704,0.6037756,0.002608765,0.04682765,0.00003898074],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945846,0.0025869,0.0003383237,0.0001434446,0.00002765366,0.00002445581,0.00005158852,0.0000206094,0.002222301],"genre_scores_gemma":[0.9986343,0.0005467919,0.0001182692,0.0000481206,0.000009865455,0.00001185453,0.0000419388,0.000002029695,0.0005867633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001121173,"threshold_uncertainty_score":0.003750682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0428168807187136,"score_gpt":0.3414093015550079,"score_spread":0.2985924208362943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}