{"id":"W4403213785","doi":"10.1021/acscatal.4c05021","title":"Synthesis of α-Quaternary Aldehydes via a Dual Ni/Rh-Catalyzed Tandem Isomerization–Propargylation Reaction","year":2024,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Kennarshore; University of Toronto","keywords":"Isomerization; Catalysis; Tandem; Chemistry; Cascade reaction; Combinatorial chemistry; Nickel; Dual (grammatical number); Organic chemistry; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000254996,0.0008208452,0.0003300542,0.0002601145,0.0001924364,0.0002905905,0.0004718902,0.0002509591,0.00190494],"category_scores_gemma":[0.0001451399,0.0002854328,0.000294246,0.0001927853,0.0002277728,0.0004474657,0.0004022547,0.001117948,0.001846871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003889327,"about_ca_system_score_gemma":0.0004738907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006399305,"about_ca_topic_score_gemma":0.00168842,"domain_scores_codex":[0.9998282,0.00001513715,0.00001608559,0.00004488726,0.00003831744,0.00005738102],"domain_scores_gemma":[0.9999094,0.000006442893,0.00001720108,0.00001329809,0.0000242062,0.00002954413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008697575,0.00005753934,0.000107049,0.0002187901,0.00002881524,0.0003405758,0.0000766923,0.0004495296,0.9854555,0.001642062,0.0004265886,0.01111004],"study_design_scores_gemma":[0.00001961156,0.0002079932,0.0002697689,0.000009869882,0.00002422002,0.0003555149,0.00002334189,0.0006284724,0.9850499,0.0001316853,0.01326179,0.0000178514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7826192,0.006085785,0.1421202,0.0007824918,0.0007431701,0.0008049428,0.001831033,0.002118474,0.06289464],"genre_scores_gemma":[0.9443917,0.003296698,0.03518106,0.0001557873,0.00005687205,0.0001022443,0.0007392938,0.0001573927,0.01591912],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00190494,"threshold_uncertainty_score":0.006372631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077947576478762,"score_gpt":0.2410667952582057,"score_spread":0.230287319493418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}