{"id":"W4403214092","doi":"10.1111/cpr.13735","title":"Functional heterogeneity of meniscal fibrochondrocytes and microtissue models is dependent on modality of fibrochondrocyte isolation","year":2024,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Edmonton Civic Employees Charitable Assistance Fund; University of Alberta; Alberta Innovates; Cliff Lede Family Charitable Foundation; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Mechanobiology; Transcriptome; Extracellular matrix; Cell biology; Collagen VI; Biology; Computational biology; Anatomy; Gene expression; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001141354,0.0001309394,0.0001189927,0.00005372543,0.00004628758,0.00002662857,0.00006292827,0.0001347053,0.00002009634],"category_scores_gemma":[0.00001336863,0.0001313775,0.00007316096,0.00005528957,0.00005541031,0.0000199093,0.00005279644,0.0000673277,0.000004470126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001575317,"about_ca_system_score_gemma":0.00006719933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004493987,"about_ca_topic_score_gemma":0.000003629394,"domain_scores_codex":[0.9990277,0.00005794987,0.0002750321,0.0003517635,0.0001816967,0.0001058551],"domain_scores_gemma":[0.9995429,0.00001455308,0.00007846092,0.0002241922,0.00008305383,0.00005685064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002594207,0.00008594953,0.0005576016,0.0002887725,0.00003158341,8.12325e-7,0.00008669766,0.002483679,0.9950362,0.0001909221,0.0004807148,0.0004976722],"study_design_scores_gemma":[0.000294217,0.000240373,0.0003347284,0.00003309205,0.00003151528,0.000006698919,0.0000119422,0.0195333,0.9783833,0.0009010083,0.000118861,0.000110984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9358481,0.002700189,0.06069672,0.0000653871,0.0000948137,0.0002474628,0.0001000426,0.00001199931,0.0002353201],"genre_scores_gemma":[0.9979367,0.00009083576,0.00105741,0.00004260163,0.0001011767,0.00001781174,0.000265319,0.00001749188,0.0004706731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06208862,"threshold_uncertainty_score":0.5357418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01461838056880963,"score_gpt":0.2458306923731481,"score_spread":0.2312123118043385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}