{"id":"W4403214092","doi":"10.1111/cpr.13735","title":"Functional heterogeneity of meniscal fibrochondrocytes and microtissue models is dependent on modality of fibrochondrocyte isolation","year":2024,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Edmonton Civic Employees Charitable Assistance Fund; University of Alberta; Alberta Innovates; Cliff Lede Family Charitable Foundation; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Mechanobiology; Transcriptome; Extracellular matrix; Cell biology; Collagen VI; Biology; Computational biology; Anatomy; Gene expression; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003925684,0.0002531684,0.0001865618,0.0003965833,0.0002049477,0.0004018042,0.0001233447,0.0001896545,0.0005672878],"category_scores_gemma":[0.0002082332,0.0001147591,0.0001733004,0.0001857827,0.0002081104,0.0002343216,0.0003198055,0.0002797892,0.0002594604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001301757,"about_ca_system_score_gemma":0.0001647474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000335243,"about_ca_topic_score_gemma":0.001115032,"domain_scores_codex":[0.9996907,0.00004116721,0.00005249283,0.00007102305,0.00009974849,0.00004499676],"domain_scores_gemma":[0.9997589,0.00006794564,0.00005468632,0.00003859055,0.00003539546,0.00004442202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005276105,0.00001565946,0.0005065537,0.00002198332,0.000003268355,0.00002737657,0.00002295251,0.00002645845,0.9983382,0.00003492755,0.000007013833,0.0009429189],"study_design_scores_gemma":[0.00001037112,0.0003930153,0.0201372,0.00001631596,0.00003201054,0.0004518235,0.0001566236,0.0008859271,0.9758202,0.00008076742,0.002005633,0.00001010732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847738,0.001346965,0.01187715,0.000041422,0.00001963366,0.00007308716,0.0003298391,0.00007988214,0.001458263],"genre_scores_gemma":[0.9887851,0.0006620279,0.007978205,0.00005644952,0.000009658959,0.0001353308,0.0006773213,0.00002937726,0.001666471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005672878,"threshold_uncertainty_score":0.002076149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01461838056880963,"score_gpt":0.2458306923731481,"score_spread":0.2312123118043385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}