{"id":"W4403221747","doi":"10.1128/spectrum.01906-24","title":"Transcriptomics identify the triggering of citrate export as the key event caused by manganese deficiency in <i>Aspergillus niger</i>","year":2024,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Debreceni Egyetem","keywords":"Citric acid; Aspergillus niger; Transcriptome; Biochemistry; Biology; Fermentation; Citric acid cycle; Downregulation and upregulation; Gene; Enzyme; Chemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004939762,0.0001878762,0.0001850945,0.00006184994,0.00006984625,0.00002463328,0.0003022504,0.0001647227,0.00002714625],"category_scores_gemma":[0.00002053865,0.0001171958,0.0001358663,0.0002488613,0.0001742434,0.000004562957,0.00004922707,0.0002316472,0.0000174864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002352486,"about_ca_system_score_gemma":0.00006009933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001015779,"about_ca_topic_score_gemma":0.0001343172,"domain_scores_codex":[0.9988264,0.00008573684,0.0003379825,0.000391825,0.00004259059,0.0003154575],"domain_scores_gemma":[0.9995397,0.000008868845,0.00005295284,0.0003568208,0.00001783312,0.00002387234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002669665,0.0000353017,0.00007532356,0.00003127681,0.00004265723,0.000005339071,0.0003214184,0.0001128202,0.9969501,0.0001270309,0.002052325,0.0002196794],"study_design_scores_gemma":[0.0001928875,0.00009307106,0.00038427,0.00002208498,0.00002604432,0.0001627545,0.00009592397,0.00001820253,0.8973103,0.00004481616,0.1015024,0.0001472729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827931,0.01388884,0.0002946312,0.001589258,0.0009797805,0.0002453308,0.00005690484,0.00002411522,0.0001280236],"genre_scores_gemma":[0.9974383,0.0009938197,0.00001279586,0.0001712681,0.0001727779,0.0000164346,0.00009974118,0.00002339732,0.001071496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09963984,"threshold_uncertainty_score":0.4779106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00490226358547625,"score_gpt":0.2222155171642421,"score_spread":0.2173132535787659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}