{"id":"W4403227134","doi":"10.1016/j.cjca.2024.08.139","title":"1-YEAR COMPARISON OF QUADRUPLE THERAPY SEQUENCING STRATEGIES FOR HEART FAILURE WITH REDUCED EJECTION FRACTION USING AN INDIVIDUAL-BASED STATE-TRANSITION MICRO-SIMULATION MODEL","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Ejection fraction; Fraction (chemistry); Heart failure; Internal medicine; Cardiology; State (computer science); Transition (genetics); Chromatography; Algorithm; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004738267,0.001126066,0.002842354,0.0007424714,0.0004269697,0.001119062,0.001509541,0.00242042,0.007032217],"category_scores_gemma":[0.01154814,0.0006531096,0.002357548,0.0004491789,0.0006168458,0.00110894,0.0008876294,0.00220534,0.0003473703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001815088,"about_ca_system_score_gemma":0.002254973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02926049,"about_ca_topic_score_gemma":0.01308482,"domain_scores_codex":[0.9990171,0.0005618434,0.00005170194,0.0001492777,0.00005168547,0.0001684029],"domain_scores_gemma":[0.9789726,0.01789298,0.0008735402,0.0003629138,0.0007008685,0.001197009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.01273625,0.001697225,0.004590268,0.0001849233,0.0007812011,0.00007941903,0.00006264016,0.9706656,0.0002528653,0.001505717,0.000695531,0.006748255],"study_design_scores_gemma":[0.001995883,0.004023928,0.004011371,0.00005261456,0.0007646866,0.00003064529,0.000092389,0.9870523,0.0002120974,0.001518242,0.0002045875,0.00004125899],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838132,0.001421944,0.01079731,0.0006724244,0.0001214511,0.0001798368,0.0009705941,0.0001201423,0.001902978],"genre_scores_gemma":[0.9967601,0.0002374958,0.001598171,0.00008556921,0.00001533791,0.0001207424,0.0004806745,0.00001189933,0.0006901767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02926049,"threshold_uncertainty_score":0.05818033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3471240651254233,"score_gpt":0.4276758194267035,"score_spread":0.08055175430128014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}