{"id":"W4403231652","doi":"10.1021/acsbiomaterials.4c01478","title":"Purified <i>Astragalus</i> Polysaccharide Combined with Inactivated Vaccine Markedly Prevents Infectious Haematopoietic Necrosis Virus Infection in Rainbow Trout (<i>Oncorhynchus mykiss</i>)","year":2024,"lang":"en","type":"article","venue":"ACS Biomaterials Science & Engineering","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Gansu Agricultural University","keywords":"Rainbow trout; Infectious hematopoietic necrosis virus; Biology; Haematopoiesis; Virology; Virus; Microbiology; Necrosis; Astragalus; Immunology; Fish <Actinopterygii>; Fishery; Stem cell; Medicine; Cell biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008217971,0.0002882206,0.0001810713,0.0002097767,0.0001132413,0.0001993901,0.00007823194,0.00009801459,0.0003652897],"category_scores_gemma":[0.00007188288,0.00007426799,0.0003931961,0.0001281507,0.0001243404,0.0001606639,0.0001706966,0.0002209807,0.00009932761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002152763,"about_ca_system_score_gemma":0.0003179717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001471723,"about_ca_topic_score_gemma":0.001969449,"domain_scores_codex":[0.9999241,0.000007344242,0.000006717978,0.0000219482,0.00002150772,0.00001845129],"domain_scores_gemma":[0.9999598,0.000002900787,0.00002135693,0.000002137609,0.000006007298,0.000007867594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001033386,0.00001443319,0.001649019,0.0000488468,0.00001543998,0.00001688301,0.000006943963,0.0002493308,0.9961185,0.00002688169,0.00005191108,0.001698447],"study_design_scores_gemma":[0.00002751482,0.001184937,0.1292277,0.00002533769,0.0001837114,0.0001898414,0.0001323436,0.008560829,0.856346,0.0001623821,0.00393932,0.00002005653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968443,0.000521536,0.001428319,0.0000412934,0.00001119519,0.00001447941,0.0005835859,0.00007756036,0.0004776517],"genre_scores_gemma":[0.9939665,0.0005701163,0.002305532,0.0000704411,0.000005423221,0.00002856051,0.002114077,0.00001846113,0.0009208699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001471723,"threshold_uncertainty_score":0.00292629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004841784427401496,"score_gpt":0.2126574069952627,"score_spread":0.2078156225678612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}