{"id":"W4403231652","doi":"10.1021/acsbiomaterials.4c01478","title":"Purified <i>Astragalus</i> Polysaccharide Combined with Inactivated Vaccine Markedly Prevents Infectious Haematopoietic Necrosis Virus Infection in Rainbow Trout (<i>Oncorhynchus mykiss</i>)","year":2024,"lang":"en","type":"article","venue":"ACS Biomaterials Science & Engineering","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Gansu Agricultural University","keywords":"Rainbow trout; Infectious hematopoietic necrosis virus; Biology; Haematopoiesis; Virology; Virus; Microbiology; Necrosis; Astragalus; Immunology; Fish <Actinopterygii>; Fishery; Stem cell; Medicine; Cell biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006643813,0.0004334142,0.0004669716,0.0007354519,0.0002119252,0.0003552932,0.0003708668,0.0001949717,0.0001542026],"category_scores_gemma":[0.00007448748,0.0003576149,0.00007820885,0.001639836,0.0001668952,0.0007693523,0.0001933928,0.0001633591,0.0001426501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002489091,"about_ca_system_score_gemma":0.000125265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007103329,"about_ca_topic_score_gemma":0.00008899454,"domain_scores_codex":[0.9978065,0.00007843254,0.0005013021,0.0007192155,0.000115721,0.0007788114],"domain_scores_gemma":[0.9993546,0.00005010188,0.0001125083,0.0003503824,0.00006188513,0.00007055002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002001169,0.0001199886,0.001160393,0.0001181443,0.0001074868,0.00004894402,0.0003449964,0.0002330265,0.9968161,0.0002478452,0.0003572807,0.0002456807],"study_design_scores_gemma":[0.00143391,0.0002464257,0.01496393,0.0004217716,0.00009290489,0.0001151648,0.00002900316,0.00004937527,0.9809696,0.00003029423,0.001212934,0.0004346838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962075,0.0004415806,0.0004978305,0.00008781993,0.00126943,0.0007328182,0.00003936191,0.0006266219,0.00009700045],"genre_scores_gemma":[0.9992129,0.000110547,0.00007001097,0.00005927215,0.00004107799,0.000104773,0.00008998383,0.00004651821,0.0002649424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01584649,"threshold_uncertainty_score":0.9998876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004841784427401496,"score_gpt":0.2126574069952627,"score_spread":0.2078156225678612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}