{"id":"W4403252024","doi":"10.3390/genes15101305","title":"PERM1—An Emerging Transcriptional Regulator of Mitochondrial Biogenesis: A Systematic Review","year":2024,"lang":"en","type":"review","venue":"Genes","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Queen's University","funders":"","keywords":"Regulator; Mitochondrial biogenesis; Biogenesis; Biology; Computational biology; Cell biology; Transcriptional regulation; Mitochondrion; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004907592,0.001225061,0.004963383,0.005305603,0.000422057,0.001935445,0.001386678,0.001441981,0.004501135],"category_scores_gemma":[0.01779936,0.0005728872,0.004386281,0.006493998,0.0006509955,0.001727732,0.001086845,0.001117119,0.000395359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002288362,"about_ca_system_score_gemma":0.01005047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004647132,"about_ca_topic_score_gemma":0.015524,"domain_scores_codex":[0.9970363,0.001164172,0.0008049799,0.0003083298,0.0005288202,0.0001574181],"domain_scores_gemma":[0.9919749,0.005929863,0.001183025,0.000130655,0.000661819,0.0001197013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.000153901,0.000009620437,0.0004885891,0.9506339,0.003844419,0.00008055061,0.0001094865,0.0001066999,0.0002297181,0.0004118969,0.0030431,0.04088803],"study_design_scores_gemma":[0.0002006731,0.0002127124,0.004087411,0.8887459,0.05035962,0.00053881,0.0002436298,0.0001270754,0.0002938223,0.0006403673,0.05451326,0.00003667227],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005286211,0.9982445,0.0001692851,0.0003197558,0.0000951716,0.0001098853,0.0003095242,0.000008131329,0.0002151695],"genre_scores_gemma":[0.007591161,0.9906825,0.0004757525,0.0005244079,0.00007608425,0.0002919117,0.0002271666,0.000004125116,0.0001268531],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005305603,"threshold_uncertainty_score":0.02595413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04384208523686296,"score_gpt":0.3323783846352408,"score_spread":0.2885362993983778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}