{"id":"W4403254218","doi":"10.1016/j.ygyno.2024.07.015","title":"Overall survival and progression-free survival by PD-L1 status among endometrial cancer patients treated with pembrolizumab plus carboplatin/paclitaxel as compared to carboplatin/paclitaxel plus placebo in the NRG GY018 trial","year":2024,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Carboplatin; Paclitaxel; Oncology; Internal medicine; Pembrolizumab; Placebo; Endometrial cancer; Progression-free survival; Overall survival; Chemotherapy; Cancer; Cisplatin; Immunotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001422998,0.0007585121,0.001790566,0.0002428301,0.0002118844,0.0006902925,0.0005337743,0.000878753,0.001645359],"category_scores_gemma":[0.001224459,0.0004020073,0.002188053,0.0003002683,0.0006199039,0.0008772801,0.0003497445,0.001980553,0.0002350668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006819265,"about_ca_system_score_gemma":0.0005810632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009669868,"about_ca_topic_score_gemma":0.00246739,"domain_scores_codex":[0.9994268,0.0003177641,0.0000340345,0.0001040961,0.0000334675,0.00008379225],"domain_scores_gemma":[0.9995213,0.0001515452,0.0001083617,0.00004968936,0.00002085444,0.0001482989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9562184,0.001526651,0.01482279,0.0003531234,0.003643432,0.00008604491,0.00008033173,0.0009419507,0.003971676,0.00009656371,0.0008189013,0.01744017],"study_design_scores_gemma":[0.6026454,0.2027746,0.1738383,0.0001503752,0.01149712,0.0002913045,0.0001979617,0.002818576,0.002083465,0.0007880804,0.00282336,0.00009146],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966941,0.002157451,0.00005992246,0.0001946376,0.00008474448,0.00006110578,0.0002793051,0.000008367289,0.0004604347],"genre_scores_gemma":[0.997879,0.0006674778,0.00009115803,0.0001866772,0.00009125962,0.0001068483,0.00045685,0.000003733182,0.0005169468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001790566,"threshold_uncertainty_score":0.007525623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02545932743865895,"score_gpt":0.333734373089856,"score_spread":0.3082750456511971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}