{"id":"W4403294439","doi":"10.1161/circresaha.124.325364","title":"Salt and CHIP: <i>Tet2</i> -CH Aggravates Salt-Sensitive Hypertension in Mice","year":2024,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Institute on Aging; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"Salt (chemistry); Internal medicine; Chemistry; Endocrinology; Medicine; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000743561,0.0002828419,0.0003484699,0.0004447267,0.0001254075,0.0001363286,0.0001824782,0.000943287,0.00001593056],"category_scores_gemma":[0.0002530278,0.0002814549,0.0001123965,0.0003922647,0.0002359053,0.000007442572,0.0002475311,0.001551118,0.00007077571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005806366,"about_ca_system_score_gemma":0.0002731826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005103956,"about_ca_topic_score_gemma":0.0002106461,"domain_scores_codex":[0.9971907,0.0003629175,0.0003208439,0.0009517613,0.0005704542,0.0006032937],"domain_scores_gemma":[0.9989073,0.0001124408,0.00006667485,0.0004338768,0.0003864608,0.00009326344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004130861,0.00001786321,0.0001409401,0.0002313371,0.00005170334,0.00008743583,0.0001115188,0.00002546662,0.4213821,0.00001445673,0.5747308,0.003165054],"study_design_scores_gemma":[0.0005197993,0.00006613726,0.003986422,0.0002101628,0.00003627338,0.0001204672,0.00005308276,0.000288785,0.01782557,0.0004889105,0.9760134,0.0003909397],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7922739,0.04966111,0.00006467623,0.1513827,0.002563365,0.001422647,0.0001892744,0.0000552878,0.002387024],"genre_scores_gemma":[0.8601062,0.01411581,0.0001318916,0.09155667,0.02243832,0.0001776875,0.003838356,0.0002655545,0.00736951],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4035565,"threshold_uncertainty_score":0.9999638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03717791682593492,"score_gpt":0.3132471987542735,"score_spread":0.2760692819283386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}