{"id":"W4403299266","doi":"10.1001/jamaoncol.2024.4376","title":"Endometrial Cancer Classification and Management in the Molecular Subtyping Era","year":2024,"lang":"en","type":"article","venue":"JAMA Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Subtyping; Endometrial biopsy; Endometrial cancer; POSTMENOPAUSAL BLEEDING; Adenocarcinoma; Biopsy; Gynecology; Vaginal bleeding; Oncology; Internal medicine; Cancer; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003144716,0.00007343026,0.000165271,0.0002369661,0.00002408577,0.00003167592,0.00005420099,0.00008187597,0.000112994],"category_scores_gemma":[0.00006451929,0.00004551574,0.00004347768,0.0006803042,0.00003686242,0.00003946829,0.0000265778,0.0001895253,0.00001962071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002733231,"about_ca_system_score_gemma":0.00006323022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001627785,"about_ca_topic_score_gemma":0.0000602196,"domain_scores_codex":[0.9992594,0.00009322196,0.0001576366,0.0002033484,0.000143339,0.0001431155],"domain_scores_gemma":[0.9995421,0.0002726456,0.00002201412,0.0001082801,0.00001588719,0.00003911811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007041114,0.0001712849,0.003570109,0.0001927218,0.0002192896,0.0009823617,0.0003859672,0.000002090044,0.001903523,0.02741324,0.001129908,0.9633254],"study_design_scores_gemma":[0.01290939,0.001123025,0.3482316,0.0002116057,0.0005690737,0.0001225329,0.0006099513,0.0006045276,0.0005225933,0.002492796,0.6324478,0.0001550169],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8489811,0.02138378,0.0001835989,0.06403203,0.001095869,0.001289082,0.000009313618,0.00006261659,0.06296256],"genre_scores_gemma":[0.9928461,0.003423075,0.0002738337,0.002635012,0.0003149126,0.0002898677,0.00001127004,0.000008248295,0.000197667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9631703,"threshold_uncertainty_score":0.1856078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04884621008771139,"score_gpt":0.3767754390035115,"score_spread":0.3279292289158001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}