{"id":"W4403307352","doi":"10.1089/crispr.2024.0032","title":"Genome Editing in Apicomplexan Parasites: Current Status, Challenges, and Future Possibilities","year":2024,"lang":"en","type":"review","venue":"The CRISPR Journal","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"","keywords":"Genome editing; Current (fluid); Biology; Genome; Computational biology; Data science; Evolutionary biology; Computer science; Genetics; Gene; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000842603,0.0004931617,0.0009946631,0.001298392,0.000227598,0.001167437,0.0007310671,0.001223931,0.00220687],"category_scores_gemma":[0.000912568,0.000234293,0.0004257032,0.001104991,0.0005005068,0.001181416,0.0005806446,0.001521975,0.0009286879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005166629,"about_ca_system_score_gemma":0.001258371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008480682,"about_ca_topic_score_gemma":0.001460757,"domain_scores_codex":[0.9997469,0.00004793873,0.00003379892,0.00003873865,0.0001024758,0.00003014406],"domain_scores_gemma":[0.9994259,0.0003330917,0.00006985285,0.00001703429,0.0001070257,0.00004723736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005748947,0.00004198593,0.0001648859,0.01856907,0.00007193424,0.0002787239,0.00009045682,0.0004257135,0.005095345,0.005754858,0.01942292,0.9500268],"study_design_scores_gemma":[0.00001115923,0.00009764652,0.0004523391,0.002827028,0.00008978863,0.001254253,0.0000749567,0.0001133343,0.001423994,0.002293055,0.9913422,0.00002023758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001912377,0.9981585,0.000233439,0.0004740243,0.0001694767,0.000003647412,0.00001449958,0.00001384072,0.0007413114],"genre_scores_gemma":[0.0009577257,0.9980004,0.0003162188,0.0002288335,0.0001027954,0.000004384623,0.0000250078,0.000002527491,0.0003620006],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00220687,"threshold_uncertainty_score":0.007382691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1005851220005584,"score_gpt":0.3925633003242125,"score_spread":0.2919781783236541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}