{"id":"W4403366781","doi":"10.1007/s12672-024-01425-y","title":"Gingerol acts as a potent radiosensitizer in head and neck squamous cell carcinoma","year":2024,"lang":"en","type":"article","venue":"Discover Oncology","topic":"Ginger and Zingiberaceae research","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canada Research Chairs","keywords":"Radiosensitizer; Basal cell; Head and neck; Medicine; Head and neck squamous-cell carcinoma; Oncology; Cancer research; Internal medicine; Radiation therapy; Head and neck cancer; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007722007,0.0002760023,0.0004125483,0.0003552084,0.000143444,0.00007806624,0.0001832741,0.0004683269,0.0006324946],"category_scores_gemma":[0.0000745195,0.0002542862,0.0001049975,0.0003329951,0.0002440879,0.0001962799,0.0001925204,0.001450637,0.0005156909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003389192,"about_ca_system_score_gemma":0.0005333931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002774225,"about_ca_topic_score_gemma":0.0001816264,"domain_scores_codex":[0.9974285,0.0006011034,0.0003419417,0.0005927279,0.0001848714,0.0008508182],"domain_scores_gemma":[0.9984688,0.0009295874,0.00004227851,0.0001925019,0.00003825536,0.0003285986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006842849,0.005322791,0.3156032,0.002681904,0.00051523,0.04998612,0.0461168,0.001901927,0.2736171,0.02038853,0.07523437,0.2017891],"study_design_scores_gemma":[0.009922842,0.002310406,0.07075023,0.00007695199,0.0002731417,0.001509084,0.001112077,0.01487461,0.0351606,0.002460929,0.8605479,0.001001234],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9392223,0.00705284,0.00001502461,0.004404518,0.001288163,0.0004664663,0.00002886106,0.00008256222,0.04743926],"genre_scores_gemma":[0.9932518,0.0003344921,0.00006315493,0.002310957,0.0003114064,0.00006262838,0.00002274664,0.0000442118,0.003598583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7853135,"threshold_uncertainty_score":0.9999909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0884869199137943,"score_gpt":0.4559686238534143,"score_spread":0.36748170393962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}