{"id":"W4403410889","doi":"10.1186/s12951-024-02926-2","title":"Colostrum-derived extracellular vesicles: potential multifunctional nanomedicine for alleviating mastitis","year":2024,"lang":"en","type":"article","venue":"Journal of Nanobiotechnology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Key Research and Development Program of China; China Agricultural University; National Natural Science Foundation of China","keywords":"Nanomedicine; Colostrum; Extracellular vesicles; Mastitis; Chemistry; Nanotechnology; Medicine; Immunology; Biology; Cell biology; Pathology; Materials science; Nanoparticle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001545002,0.0002424285,0.0001552111,0.0001453454,0.00009378255,0.0002988441,0.0001199038,0.0004290966,0.0004414335],"category_scores_gemma":[0.000105386,0.00006764576,0.0001881066,0.00007865,0.0001446952,0.0003063476,0.0002499236,0.0002735683,0.0001190606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000190428,"about_ca_system_score_gemma":0.0001232455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002112981,"about_ca_topic_score_gemma":0.0004146147,"domain_scores_codex":[0.9999384,0.00001596909,0.000003502664,0.00001103458,0.00001312995,0.00001810877],"domain_scores_gemma":[0.9999673,0.000006992646,0.00001103341,0.000001632332,0.000005586722,0.000007401218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001322965,0.00003080998,0.0002641766,0.0003080213,0.00001839676,0.0001565621,0.00002364152,0.0004242254,0.98518,0.0004862113,0.000237796,0.01273792],"study_design_scores_gemma":[0.00004249245,0.0009519534,0.002764507,0.00008266566,0.0000836827,0.0007687837,0.00008013492,0.00389297,0.9613771,0.0003163213,0.02961754,0.00002176601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9081579,0.06020604,0.02493377,0.001111114,0.0003263572,0.0001244877,0.0004392936,0.0001271704,0.004573824],"genre_scores_gemma":[0.9830125,0.009925928,0.005105794,0.0002362214,0.000032059,0.00004256376,0.0001544114,0.00001168656,0.001478891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004414335,"threshold_uncertainty_score":0.001476765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007656108277791919,"score_gpt":0.2444281940359684,"score_spread":0.2367720857581765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}