{"id":"W4403417775","doi":"10.1038/s41380-024-02731-1","title":"The genetics of severe depression","year":2024,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"The Wellcome Trust DBT India Alliance; National Institute of Mental Health; U.S. Department of Health and Human Services","keywords":"Depression (economics); Psychology; Psychiatry; Genetics; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001274354,0.001522043,0.002176969,0.002283795,0.0002709649,0.001295917,0.001347303,0.002299601,0.002675425],"category_scores_gemma":[0.001909472,0.0004408762,0.0005858545,0.002177697,0.001006534,0.001220283,0.001163045,0.003384677,0.001610361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001115733,"about_ca_system_score_gemma":0.001634196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002187405,"about_ca_topic_score_gemma":0.004174116,"domain_scores_codex":[0.9996256,0.0001057473,0.00004613278,0.00006533445,0.0001264387,0.00003072942],"domain_scores_gemma":[0.9992417,0.0004585689,0.00007967834,0.00002658736,0.0001251713,0.00006821895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001335405,0.00006221009,0.0004624289,0.008125595,0.0002299889,0.0004299904,0.00004165525,0.000454925,0.0006687277,0.008158024,0.1464651,0.8347678],"study_design_scores_gemma":[0.00007444184,0.00006227915,0.001846538,0.005715146,0.000244137,0.002152048,0.00006922555,0.0002140224,0.0001408333,0.01090119,0.9785467,0.000033647],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000205791,0.9983292,0.00009779884,0.0006752253,0.0004826929,0.000001813835,0.00001182401,0.00000337578,0.0003775276],"genre_scores_gemma":[0.0002485951,0.9972014,0.0001232279,0.0006064035,0.001419812,0.000003967873,0.0000289266,0.000001083911,0.0003666164],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002675425,"threshold_uncertainty_score":0.008950174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01443645543565526,"score_gpt":0.3252205449652825,"score_spread":0.3107840895296272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}