{"id":"W4403418499","doi":"10.7554/elife.101125.1","title":"Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Effector; Amidase; Type VI secretion system; Biology; Bacillus subtilis; Secretion; Cell biology; Peptidoglycan; Microbiology; Genetics; Biochemistry; Bacteria; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001440835,0.000286395,0.0001780583,0.000152469,0.0000690227,0.0002938221,0.0001711843,0.0003062294,0.0005105012],"category_scores_gemma":[0.000125624,0.00007604335,0.0002424077,0.000142811,0.0001731504,0.0002372427,0.0003095625,0.0004603015,0.0002530401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001704143,"about_ca_system_score_gemma":0.00008199662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001128108,"about_ca_topic_score_gemma":0.00009234158,"domain_scores_codex":[0.9999154,0.00001458724,0.000009291883,0.00001452804,0.00002877024,0.00001748563],"domain_scores_gemma":[0.99992,0.00001448652,0.00002208859,0.00001218153,0.00001322762,0.00001797928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000375846,0.00001114237,0.0002853567,0.000009136385,0.000002545609,0.0001029497,0.000008364213,0.00009213801,0.9984268,0.0001603098,0.00001312513,0.0008506064],"study_design_scores_gemma":[0.000009132313,0.0002071893,0.003298851,0.000003697389,0.00001271136,0.0008803504,0.00003043726,0.002523253,0.9903173,0.0001165653,0.002594559,0.000005812318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915313,0.0003325449,0.007396899,0.00004741077,0.000009202942,0.00001477334,0.0001167912,0.00005638276,0.0004947173],"genre_scores_gemma":[0.9938425,0.000162044,0.00431012,0.00002583581,0.000004830461,0.00001438922,0.0003488683,0.00001335731,0.001278035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005105012,"threshold_uncertainty_score":0.001707852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0154711574640938,"score_gpt":0.281424101964892,"score_spread":0.2659529445007982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}