{"id":"W4403424440","doi":"10.1513/annalsats.202403-238oc","title":"Genomic and Serological Rheumatoid Arthritis Biomarkers, <i>MUC5B</i> Promoter Variant, and Interstitial Lung Abnormalities","year":2024,"lang":"en","type":"article","venue":"Annals of the American Thoracic Society","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Environmental Health Sciences; National Human Genome Research Institute; U.S. Department of Defense; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Kennedy Trust for Rheumatology Research","keywords":"Medicine; Rheumatoid arthritis; Serology; Lung; Immunology; Pathology; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008462718,0.0004714972,0.0004227365,0.0007958933,0.0003195537,0.0006358563,0.0004256601,0.0004940722,0.002872602],"category_scores_gemma":[0.002194051,0.0001708444,0.0005895247,0.001063501,0.000379232,0.000260213,0.0004113131,0.0004544164,0.0002340657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760347,"about_ca_system_score_gemma":0.0002752012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003210221,"about_ca_topic_score_gemma":0.002591471,"domain_scores_codex":[0.9992773,0.0002523338,0.00008064033,0.000227201,0.00008853999,0.00007400581],"domain_scores_gemma":[0.9980807,0.0004362535,0.0009963645,0.0001505955,0.00009626296,0.0002398046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002924729,0.00001221589,0.9973248,0.00001699881,0.0001966423,0.00006797999,0.00001185611,0.00007604124,0.001065283,0.00002995146,0.00005662644,0.0008490953],"study_design_scores_gemma":[0.00001496637,0.0001059834,0.9977366,0.00001219853,0.0002140578,0.0006879019,0.00004181121,0.0005264161,0.000317662,0.0001177953,0.0002202768,0.000004297491],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970382,0.001086181,0.0004776996,0.000110804,0.00001013803,0.000007778782,0.0007419621,0.00001162487,0.0005155624],"genre_scores_gemma":[0.9992346,0.00008736997,0.0002527331,0.00003043711,0.00001400499,0.000005599424,0.0002533507,0.000002019396,0.0001198871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003210221,"threshold_uncertainty_score":0.009609878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05627162655172632,"score_gpt":0.3765090180264413,"score_spread":0.320237391474715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}