{"id":"W4403433218","doi":"10.1016/j.pharma.2024.10.002","title":"Development and in vitro-in vivo evaluation of ocular insert containing ketorolac tromethamine and moxifloxacin hydrochloride","year":2024,"lang":"en","type":"article","venue":"Annales Pharmaceutiques Françaises","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hatch (Canada)","funders":"Saurashtra University","keywords":"Ketorolac Tromethamine; Insert (composites); In vivo; Ketorolac; Moxifloxacin; Pharmacology; In vitro; Medicine; Chemistry; Materials science; Biology; Analgesic; Composite material","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003185477,0.0003397579,0.0005239623,0.0006003185,0.00009431592,0.00002793797,0.0001418752,0.0002417803,0.0001425033],"category_scores_gemma":[0.0001322707,0.0003477771,0.00005519527,0.0004368496,0.0002283676,0.000452596,0.000101384,0.0006285476,0.00000872974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001599532,"about_ca_system_score_gemma":0.0002035668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008057679,"about_ca_topic_score_gemma":0.0001984295,"domain_scores_codex":[0.9972032,0.0006501795,0.0007837391,0.0005522248,0.0003690933,0.0004415779],"domain_scores_gemma":[0.998851,0.000582213,0.0001289268,0.0001331981,0.0001298438,0.000174801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001768379,0.0002184059,0.02856417,0.0007433792,0.0002628807,0.0002123073,0.01422319,0.001443946,0.782538,0.0001316449,0.0001133721,0.1697803],"study_design_scores_gemma":[0.002553756,0.00005957905,0.003170023,0.0002563193,0.0001398781,0.00004543414,0.0007548318,0.06917006,0.7849327,0.0001086933,0.1384359,0.0003727624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.936548,0.06106636,0.00006098267,0.0001725435,0.0003844279,0.0007566403,0.00003679452,0.00008909764,0.0008851683],"genre_scores_gemma":[0.9955407,0.003078958,0.0005969186,0.0003458909,0.00009138889,0.0001954465,0.00001927554,0.00004001791,0.00009135151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1694075,"threshold_uncertainty_score":0.9998974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1422798461114077,"score_gpt":0.4445671025555749,"score_spread":0.3022872564441672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}