{"id":"W4403463896","doi":"10.1053/j.ajkd.2024.08.008","title":"Treatment of Autosomal-Dominant Polycystic Kidney Disease","year":2024,"lang":"en","type":"review","venue":"American Journal of Kidney Diseases","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Otsuka America","keywords":"Medicine; Autosomal dominant polycystic kidney disease; Polycystic kidney; Polycystic kidney disease; Kidney disease; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004085764,0.0006551445,0.001250857,0.00113565,0.0002105618,0.0005785457,0.0009407986,0.0008767821,0.002941492],"category_scores_gemma":[0.000616655,0.0001613066,0.0007324803,0.0007533191,0.0002415734,0.0005708464,0.0005033094,0.002052233,0.001423125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004494493,"about_ca_system_score_gemma":0.000443255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008290909,"about_ca_topic_score_gemma":0.00154253,"domain_scores_codex":[0.9997985,0.00004469337,0.00002598749,0.00003178309,0.00007873789,0.00002027293],"domain_scores_gemma":[0.9998453,0.00006578754,0.00002665967,0.000005102889,0.00004013925,0.00001695112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001363986,0.00008690676,0.00009980353,0.009315541,0.000147098,0.0001414458,0.00002332719,0.0003005192,0.0008685577,0.001567511,0.03830462,0.9490084],"study_design_scores_gemma":[0.000110343,0.0001796898,0.001458773,0.006593804,0.0001976852,0.001850061,0.00003810342,0.0001955991,0.0005925466,0.002018373,0.9867437,0.00002142645],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001554956,0.998363,0.0001258041,0.0002577704,0.0002504399,0.000004674319,0.0000194051,0.00001082008,0.0008126791],"genre_scores_gemma":[0.001307295,0.9972724,0.0001937639,0.000289124,0.0001797842,0.000009662894,0.0000532448,0.000002397285,0.0006923712],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002941492,"threshold_uncertainty_score":0.00984025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241057431578546,"score_gpt":0.3017563256277325,"score_spread":0.289345751311947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}