{"id":"W4403482962","doi":"10.1111/his.15346","title":"Discordance of human epidermal growth factor receptor 2‐low status between breast primary and distant metastases with clinical–pathological correlation","year":2024,"lang":"en","type":"article","venue":"Histopathology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Pathological; Human Epidermal Growth Factor Receptor 2; Medicine; Oncology; Primary (astronomy); Correlation; Pathology; Epidermal growth factor receptor; Epidermal growth factor; Internal medicine; Receptor; Breast cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008492388,0.0001971848,0.0002486503,0.0009135668,0.0002747353,0.0005704008,0.0003152222,0.0002909714,0.003394821],"category_scores_gemma":[0.002816307,0.0001375392,0.0001726152,0.0004898151,0.000460994,0.0002814952,0.0004921392,0.0001774276,0.0005301173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002806082,"about_ca_system_score_gemma":0.0001570048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005854691,"about_ca_topic_score_gemma":0.0008581141,"domain_scores_codex":[0.999455,0.0001241898,0.00009668552,0.0001287027,0.0001051798,0.00009020818],"domain_scores_gemma":[0.9982052,0.0006107212,0.0006121807,0.0001309613,0.0002303261,0.0002105419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002025067,0.000008692698,0.9968621,0.00001168855,0.00001515134,0.0003202302,0.00003372663,0.0000183417,0.001433206,0.00001242498,0.00003343237,0.001048575],"study_design_scores_gemma":[0.00001107062,0.0001226284,0.99319,0.000006742608,0.00003348005,0.00473145,0.0001494901,0.0001786048,0.00128932,0.00004509548,0.0002385587,0.000003549102],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990663,0.0002574924,0.0001230973,0.00001091584,0.000004237339,0.000006296931,0.0000711689,0.000002763874,0.0004576866],"genre_scores_gemma":[0.9997657,0.000027669,0.00005001844,0.000005053827,0.000004214106,0.000003491272,0.00007750694,7.661265e-7,0.00006571934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003394821,"threshold_uncertainty_score":0.01135677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01837121203749709,"score_gpt":0.2918271277146801,"score_spread":0.273455915677183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}