{"id":"W4403482962","doi":"10.1111/his.15346","title":"Discordance of human epidermal growth factor receptor 2‐low status between breast primary and distant metastases with clinical–pathological correlation","year":2024,"lang":"en","type":"article","venue":"Histopathology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Pathological; Human Epidermal Growth Factor Receptor 2; Medicine; Oncology; Primary (astronomy); Correlation; Pathology; Epidermal growth factor receptor; Epidermal growth factor; Internal medicine; Receptor; Breast cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001747301,0.000230647,0.0004513261,0.00005345005,0.00009806313,0.00001155337,0.00009008741,0.0001387631,0.00002576571],"category_scores_gemma":[0.00004896818,0.0001702719,0.00009488333,0.0000869209,0.0007583782,0.00001123452,0.0001303865,0.0001531331,0.000004741952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004909197,"about_ca_system_score_gemma":0.00006613291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003355545,"about_ca_topic_score_gemma":0.00002683917,"domain_scores_codex":[0.9984133,0.0001840449,0.0004058968,0.0006084992,0.0001102435,0.0002780436],"domain_scores_gemma":[0.9993483,0.00009641466,0.000145781,0.0002481524,0.00006880306,0.00009258455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004113157,0.0001950378,0.928767,0.0001935671,0.00009346597,0.0001217806,0.0002221469,0.000002043913,0.05928766,0.001239695,0.0004245296,0.009041799],"study_design_scores_gemma":[0.0006102695,0.0007798036,0.9945042,0.00004793617,0.0001421868,0.0001693749,0.00004578675,0.000002253868,0.001634067,0.0001313407,0.001726654,0.000206158],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914333,0.00422824,0.002376626,0.0002047152,0.0002492724,0.0001797325,0.0009940364,0.00003639495,0.0002976593],"genre_scores_gemma":[0.9973882,0.0004512141,0.001023754,0.00005795594,0.0002036571,0.0000362127,0.0006598363,0.00002771653,0.0001514319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06573721,"threshold_uncertainty_score":0.6943487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01837121203749709,"score_gpt":0.2918271277146801,"score_spread":0.273455915677183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}