{"id":"W4403496545","doi":"10.26434/chemrxiv-2024-3g44k-v2","title":"The origin of pressure resistance in deep-sealactate dehydrogenase","year":2024,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Methane Hydrates and Related Phenomena","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Island University","funders":"","keywords":"Lactate dehydrogenase; Resistance (ecology); L-Lactate dehydrogenase; Chemistry; Biology; Biochemistry; Ecology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009697835,0.0002673168,0.0002348844,0.0001819041,0.0002773955,0.0003752677,0.0003060808,0.0003213419,0.0007859329],"category_scores_gemma":[0.0003591556,0.0002191316,0.0002722556,0.0001639958,0.000528118,0.0003484561,0.0004255901,0.0003403734,0.00007268487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004231423,"about_ca_system_score_gemma":0.0002868355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003462151,"about_ca_topic_score_gemma":0.002284301,"domain_scores_codex":[0.999951,0.00000605376,0.00000344225,0.00001121659,0.00001205942,0.00001623737],"domain_scores_gemma":[0.9999336,0.00001628695,0.00001877515,0.000006168686,0.00001033317,0.0000147412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000432937,0.0001680544,0.0668873,0.0002436409,0.0001574855,0.0008842626,0.0006094038,0.07569206,0.8441836,0.004788898,0.0002570121,0.005695438],"study_design_scores_gemma":[0.0001637467,0.0005924728,0.1954864,0.00003766566,0.00009708633,0.0004635402,0.0007301439,0.6167689,0.1789363,0.005051849,0.001575133,0.00009679438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992465,0.00005033379,0.0003737988,0.00003703263,0.000002372095,0.000001943933,0.00003717485,0.00001086858,0.0002400112],"genre_scores_gemma":[0.9996307,0.00003605584,0.0002147736,0.000005721247,8.843431e-7,0.000002648809,0.00004182966,0.000005323617,0.00006223615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003462151,"threshold_uncertainty_score":0.006884038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01203037649726844,"score_gpt":0.2388850502756547,"score_spread":0.2268546737783863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}