{"id":"W4403500339","doi":"10.1016/j.jaad.2024.09.064","title":"Sustained hair regrowth with continued ritlecitinib treatment through week 48 in patients with alopecia areata with or without early target responses: Post hoc analysis of the ALLEGRO phase 2b/3 trial","year":2024,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Pfizer","keywords":"Alopecia areata; Medicine; Post-hoc analysis; Dermatology; Post hoc; Hair growth; Hair loss; Internal medicine; Physiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002074092,0.0003319257,0.001793833,0.000590356,0.00006801598,0.00001798798,0.0004224286,0.0001047543,0.00003551119],"category_scores_gemma":[0.000214259,0.0001339691,0.0003486755,0.002286167,0.001130947,0.0001931872,0.00006021864,0.0005607064,9.055571e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001258881,"about_ca_system_score_gemma":0.0008673915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000201768,"about_ca_topic_score_gemma":0.0001630418,"domain_scores_codex":[0.9971305,0.0005508134,0.0009597075,0.0002891512,0.000672095,0.0003977429],"domain_scores_gemma":[0.9976295,0.0003885168,0.001271992,0.000325725,0.0002414919,0.0001427735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5381833,0.001737371,0.4485749,0.00008398313,0.005605468,0.0003193486,0.003455536,0.00003416347,0.0001062728,0.00008539862,0.0008768126,0.0009375218],"study_design_scores_gemma":[0.3200268,0.0629199,0.5690686,0.001697285,0.01532013,0.002249741,0.01566003,0.0003759824,0.002988922,0.0001624396,0.008722492,0.000807737],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986825,0.0003016987,0.0001233736,0.01147107,0.00005044552,0.0009264117,0.00009423125,0.00001329629,0.0001944129],"genre_scores_gemma":[0.9978658,0.00007342005,0.00091083,0.0008111809,0.00004720656,0.00001700127,0.00001003296,0.00003976751,0.0002247558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2181565,"threshold_uncertainty_score":0.5463102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01568490326520126,"score_gpt":0.3174311889314136,"score_spread":0.3017462856662123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}