{"id":"W4403500339","doi":"10.1016/j.jaad.2024.09.064","title":"Sustained hair regrowth with continued ritlecitinib treatment through week 48 in patients with alopecia areata with or without early target responses: Post hoc analysis of the ALLEGRO phase 2b/3 trial","year":2024,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Pfizer","keywords":"Alopecia areata; Medicine; Post-hoc analysis; Dermatology; Post hoc; Hair growth; Hair loss; Internal medicine; Physiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003940399,0.0007366704,0.002059213,0.0002652604,0.0002819908,0.0008357044,0.000520235,0.0005702771,0.003352061],"category_scores_gemma":[0.001794457,0.0002553074,0.003112022,0.000254838,0.0004022572,0.0009184395,0.0002974688,0.001916755,0.0005681607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006012013,"about_ca_system_score_gemma":0.0009133853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004649754,"about_ca_topic_score_gemma":0.001975743,"domain_scores_codex":[0.9988317,0.000683057,0.00006432246,0.0001623482,0.0001022073,0.0001564429],"domain_scores_gemma":[0.9984162,0.0005422723,0.0004585282,0.0001542611,0.0001060775,0.0003226681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.8930455,0.005647233,0.01472096,0.001049403,0.005466644,0.0001055984,0.0001415252,0.001702575,0.009022051,0.00006943533,0.001943849,0.06708524],"study_design_scores_gemma":[0.5115918,0.3768401,0.09587394,0.0001133123,0.005724364,0.0003700021,0.0000936001,0.002828821,0.00302942,0.0002746384,0.003201561,0.00005848871],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939039,0.003398847,0.0002909401,0.000234536,0.00005706551,0.0005443129,0.0005692443,0.00007467609,0.0009263839],"genre_scores_gemma":[0.9972706,0.0006050454,0.0003636279,0.0001688235,0.00006866812,0.0004615326,0.0005187583,0.00001369964,0.0005291727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003940399,"threshold_uncertainty_score":0.0208391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01568490326520126,"score_gpt":0.3174311889314136,"score_spread":0.3017462856662123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}