{"id":"W4403511685","doi":"10.1093/neuonc/noae144.013","title":"KS03.5.A EVALUATION OF VAL-083 IN GBM AGILE, A PHASE 3 REGISTRATION PLATFORM TRIAL FOR NEWLY DIAGNOSED AND RECURRENT GLIOBLASTOMA","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; McGill University Health Centre; University of Toronto","funders":"","keywords":"Glioblastoma; Agile software development; Medicine; Phase (matter); Oncology; Cancer research; Medical physics; Internal medicine; Computer science; Software engineering; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001556693,0.0007772357,0.000910007,0.0003202021,0.0002684757,0.0008186178,0.0006760081,0.0006454773,0.008071],"category_scores_gemma":[0.001089053,0.0002286821,0.001217203,0.000349071,0.0004720445,0.000575121,0.0003546273,0.002119137,0.001159048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008191511,"about_ca_system_score_gemma":0.001674568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001515913,"about_ca_topic_score_gemma":0.005036491,"domain_scores_codex":[0.9995427,0.0002678123,0.0000202161,0.000054676,0.00004490201,0.00006968142],"domain_scores_gemma":[0.9994585,0.00007948453,0.0001377984,0.00004417938,0.00004755685,0.0002324828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6762084,0.01354614,0.00465293,0.002079424,0.002066567,0.0001983779,0.0002107436,0.005085743,0.02099009,0.002285579,0.02961825,0.2430577],"study_design_scores_gemma":[0.6865289,0.2630579,0.01584083,0.0003095625,0.001481932,0.0004068231,0.00015178,0.005425496,0.00500291,0.002667001,0.01904437,0.00008254145],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9630422,0.006915729,0.002132479,0.002492695,0.0004098725,0.003189819,0.00815779,0.0008038322,0.01285553],"genre_scores_gemma":[0.9767057,0.002797211,0.00297509,0.002081739,0.000163283,0.002791774,0.005814592,0.000112396,0.006558207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008071,"threshold_uncertainty_score":0.02700019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07161932857619517,"score_gpt":0.400097296983522,"score_spread":0.3284779684073268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}