{"id":"W4403520285","doi":"10.1158/2326-6074.tumimm24-b012","title":"Abstract B012: Reviving exhausted T cells in pediatric B-cell acute lymphoblastic leukemia","year":2024,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Lymphoblastic Leukemia; Medicine; Cancer research; Immunology; Leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.002223854,0.0003038883,0.0005830525,0.001917162,0.0001574759,0.0001339309,0.0005673095,0.0004660408,0.01005805],"category_scores_gemma":[0.0001884144,0.0002783864,0.0001812038,0.002946602,0.0004803791,0.0001786453,0.0003735065,0.003002789,0.001762626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003506647,"about_ca_system_score_gemma":0.003787477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001063479,"about_ca_topic_score_gemma":0.0001037464,"domain_scores_codex":[0.995566,0.0003382041,0.0005792917,0.0009219158,0.0009581577,0.001636464],"domain_scores_gemma":[0.9972673,0.001230179,0.00004566561,0.0008383892,0.0003804426,0.0002380234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001110833,0.0001710868,0.00571847,0.00135888,0.000293258,0.00253901,0.0005927523,0.00003288306,0.9424049,0.00003976973,0.01190887,0.03382923],"study_design_scores_gemma":[0.01682851,0.002863702,0.2994169,0.003708868,0.0005621637,0.0007469696,0.001327204,0.003595626,0.4866822,0.0005007991,0.181992,0.001775127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.932636,0.05076272,0.000008222287,0.000945251,0.0008409575,0.001059453,0.0000260279,0.0001602674,0.01356114],"genre_scores_gemma":[0.9057186,0.0491289,0.00004192682,0.00007242505,0.0007369517,0.0004078076,0.00002348671,0.0001213122,0.04374859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4557227,"threshold_uncertainty_score":0.9999669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05261392441516446,"score_gpt":0.3874645670991617,"score_spread":0.3348506426839973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}