{"id":"W4403542768","doi":"10.1152/ajpheart.00322.2024","title":"Serial and regional assessment of the right ventricular molecular and functional response to pressure loading","year":2024,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Pressure overload; Medicine; Muscle hypertrophy; Fibrosis; Internal medicine; Cardiology; Inflammation; Ventricular remodeling; Endocrinology; Chemokine; Sham surgery; Pathology; Heart failure; Cardiac hypertrophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007576249,0.0004176582,0.0005907315,0.0004538878,0.0002156688,0.0008080504,0.0002891462,0.0005636335,0.002543085],"category_scores_gemma":[0.0006518256,0.0002210323,0.0002432326,0.0002669463,0.00057875,0.000824644,0.0003751225,0.001573382,0.0005156533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001409094,"about_ca_system_score_gemma":0.0003845585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004209149,"about_ca_topic_score_gemma":0.0009150865,"domain_scores_codex":[0.999683,0.00006406713,0.00002064983,0.0001045086,0.00006778644,0.00005993885],"domain_scores_gemma":[0.9993974,0.0001004084,0.0001499164,0.00009903836,0.00009763281,0.000155748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00129106,0.0001752362,0.01401021,0.000164806,0.00007960646,0.0001439804,0.0001059049,0.000346637,0.9645907,0.000288333,0.0003918535,0.01841177],"study_design_scores_gemma":[0.00009685621,0.00570932,0.6128614,0.0001063915,0.0003735231,0.001175288,0.0006403896,0.005196583,0.3683497,0.001240492,0.004141422,0.0001086814],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9510821,0.005684003,0.03734992,0.0003519408,0.0002099982,0.0001760505,0.00120988,0.0003560387,0.003580097],"genre_scores_gemma":[0.9821883,0.003032578,0.01026511,0.0002387725,0.0001809246,0.000276198,0.0008164063,0.00009041284,0.002911396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002543085,"threshold_uncertainty_score":0.00850749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01282986058578451,"score_gpt":0.2827304796530096,"score_spread":0.2699006190672251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}