{"id":"W4403592169","doi":"10.1016/j.fertnstert.2024.08.287","title":"ALPHASPERM-INDUCED EPIGENETIC REPROGRAMMING IN SPERM","year":2024,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Decipher Biosciences (Canada)","funders":"","keywords":"Reprogramming; Epigenetics; Sperm; Andrology; Biology; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001555102,0.0001393074,0.0001316789,0.000185646,0.0001201453,0.0002620166,0.0001683277,0.0002005594,0.002865057],"category_scores_gemma":[0.0001095335,0.0001037424,0.0001954847,0.0001282977,0.0001504692,0.000171934,0.0002397589,0.0004123213,0.0004859155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001877138,"about_ca_system_score_gemma":0.0001312654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001904594,"about_ca_topic_score_gemma":0.0003568925,"domain_scores_codex":[0.9999267,0.00001506585,0.000005200287,0.00001686359,0.00002023164,0.00001591147],"domain_scores_gemma":[0.9999504,0.00001305444,0.0000118677,0.0000108948,0.00000527056,0.000008529922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006655757,0.000008988975,0.0002973769,0.00002806646,0.000005688334,0.00009534087,0.00001654957,0.00005554918,0.9939501,0.0009382279,0.00006228931,0.004475259],"study_design_scores_gemma":[0.00002156877,0.0001986899,0.01468945,0.00001417057,0.00002469619,0.0006484485,0.000049441,0.0005938332,0.9727582,0.0004170344,0.01057849,0.000005887673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9718145,0.005115044,0.005892308,0.0002842202,0.0001746987,0.00003303242,0.0006016067,0.0001506384,0.01593401],"genre_scores_gemma":[0.988613,0.001130141,0.0007594418,0.00008545065,0.00002001756,0.000007897841,0.000319742,0.00001788886,0.009046461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002865057,"threshold_uncertainty_score":0.009584546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02722137593604927,"score_gpt":0.3054517282255627,"score_spread":0.2782303522895134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}