{"id":"W4403597865","doi":"10.1093/bioinformatics/btae622","title":"Biologically-informed killer cell immunoglobulin-like receptor gene annotation tool","year":2024,"lang":"en","type":"article","venue":"Bioinformatics","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Cancer Institute; National Institutes of Health","keywords":"Genotyping; Annotation; Computational biology; Computer science; Gene; Identification (biology); Biology; Genetics; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002063739,0.0002220415,0.0002010862,0.000178566,0.0001868837,0.0001102073,0.00017123,0.0003347055,0.004225299],"category_scores_gemma":[0.00006911649,0.000170351,0.0001570649,0.0002274561,0.00008854285,0.0005329357,0.00006873092,0.00034194,0.02643953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001230787,"about_ca_system_score_gemma":0.0001135687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001171749,"about_ca_topic_score_gemma":7.476846e-7,"domain_scores_codex":[0.9987575,0.00004556743,0.0006505063,0.0001608678,0.00005307326,0.0003324948],"domain_scores_gemma":[0.9993635,0.000138335,0.0001323351,0.0002607892,0.00008493801,0.00002004223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003300871,0.00014279,0.0001286197,0.0002854177,0.000300517,0.000003128329,0.002667187,0.00003634491,0.2767324,0.001085755,0.6780381,0.04024967],"study_design_scores_gemma":[0.0005278205,0.0002175252,0.0003979324,0.00005189865,0.00003479727,0.00005227014,0.0004928233,0.0007373379,0.06286163,0.00002017054,0.9343454,0.0002603789],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6025389,0.02060013,0.04043614,0.002421724,0.1622113,0.002802754,0.0001910999,0.004154663,0.1646433],"genre_scores_gemma":[0.779688,0.003270865,0.0119675,0.003885293,0.0003373793,0.0001352305,0.006762415,0.00008119414,0.1938721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2563073,"threshold_uncertainty_score":0.996685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0134903828001199,"score_gpt":0.2365378545879528,"score_spread":0.2230474717878329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}