{"id":"W4403604899","doi":"10.58931/cot.2024.1222","title":"From Intractable to Treatable: Milestones and Horizons in the Management of HER2+ Breast Cancer","year":2024,"lang":"en","type":"article","venue":"Canadian oncology today.","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Breast cancer; Medicine; New horizons; Cancer; General surgery; Internal medicine; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002796656,0.0006826213,0.000748902,0.0008527137,0.000928487,0.002999823,0.001258482,0.002558089,0.009611985],"category_scores_gemma":[0.005441749,0.0001861792,0.0005763768,0.0005739527,0.002124764,0.006000353,0.002990318,0.009983575,0.003194473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002063934,"about_ca_system_score_gemma":0.003302099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001428259,"about_ca_topic_score_gemma":0.004843989,"domain_scores_codex":[0.9987655,0.0004205368,0.0001011831,0.0001369882,0.0004263774,0.0001494086],"domain_scores_gemma":[0.9977334,0.00060382,0.0002173212,0.00008070972,0.0005413886,0.0008234185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002201353,0.0002249226,0.0007955355,0.002293408,0.00003710673,0.0006791956,0.0005252545,0.0004404355,0.001094388,0.0303862,0.4182123,0.5450911],"study_design_scores_gemma":[0.00004620308,0.000221848,0.0008529457,0.004049534,0.00002879403,0.001667405,0.0006265174,0.0002673133,0.0002695237,0.02424528,0.9676916,0.00003297092],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002210827,0.603322,0.00383108,0.358123,0.01484979,0.00005159143,0.0001562563,0.0001638543,0.01729168],"genre_scores_gemma":[0.03015422,0.8076773,0.00628631,0.1209697,0.02292386,0.00009977695,0.0003751682,0.0001142669,0.01139933],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009611985,"threshold_uncertainty_score":0.03215533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02702545990048791,"score_gpt":0.3752658411589677,"score_spread":0.3482403812584798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}