{"id":"W4403622162","doi":"10.58931/cht.2023.2342","title":"Chimeric antigen receptor (CAR) T-cell therapy in multiple myeloma: The evolving Canadian landscape","year":2023,"lang":"en","type":"article","venue":"Canadian Hematology Today","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Gilead Sciences; Sanofi","keywords":"Chimeric antigen receptor; Multiple myeloma; Antigen; Immunology; Receptor; Medicine; Cancer research; Virology; Biology; Immunotherapy; Internal medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006274331,0.0004954903,0.0007744834,0.002090832,0.002220613,0.003055415,0.001586562,0.002205087,0.01097903],"category_scores_gemma":[0.006724352,0.0002128593,0.0004472387,0.004111651,0.003496171,0.002300664,0.001845725,0.004040285,0.00163429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.02738625,"about_ca_system_score_gemma":0.04924434,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.4278964,"about_ca_topic_score_gemma":0.6190782,"domain_scores_codex":[0.9979782,0.0003780237,0.0001201688,0.0002334293,0.0009601635,0.0003300085],"domain_scores_gemma":[0.9927597,0.001267202,0.0003740377,0.0001056845,0.004038124,0.001455278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006129391,0.0002241094,0.002508467,0.002159182,0.00009710116,0.000458862,0.0003851192,0.001236331,0.001964833,0.05551614,0.1888339,0.7460031],"study_design_scores_gemma":[0.0001674587,0.0002836081,0.00308611,0.001484023,0.0001126169,0.0006127977,0.0004826794,0.0006002003,0.000752785,0.006602238,0.9857686,0.00004695047],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00542839,0.7127001,0.001614597,0.2474798,0.003493699,0.0000477627,0.0003444029,0.0001244319,0.02876692],"genre_scores_gemma":[0.06279214,0.8873407,0.002804045,0.03378167,0.003504518,0.00006161958,0.0003840411,0.00008693981,0.00924418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5721036,"threshold_uncertainty_score":0.8508115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02781133904866197,"score_gpt":0.2724164986273658,"score_spread":0.2446051595787038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}