{"id":"W4403622168","doi":"10.58931/cht.2024.3s01-244","title":"Navigating the Paradigm Shift in Chronic Lymphocytic Leukemia Treatment from Chemotherapy to Targeted Therapies","year":2024,"lang":"en","type":"article","venue":"Canadian Hematology Today","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Paradigm shift; Chronic lymphocytic leukemia; Chemotherapy; Medicine; Oncology; Leukemia; Intensive care medicine; Internal medicine; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01073574,0.0004333325,0.001216021,0.001892641,0.003179003,0.006125846,0.002511052,0.002344139,0.004190291],"category_scores_gemma":[0.01007223,0.0002534766,0.0006638875,0.002939486,0.005294419,0.002779637,0.00272007,0.006855345,0.001073541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.03931568,"about_ca_system_score_gemma":0.1296213,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.5739254,"about_ca_topic_score_gemma":0.8113444,"domain_scores_codex":[0.9925457,0.002378336,0.0005277718,0.0003619851,0.003147733,0.001038488],"domain_scores_gemma":[0.9909309,0.00189113,0.00047396,0.0001628983,0.005184515,0.001356702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002253576,0.00008748008,0.002085209,0.009074621,0.0001372544,0.00128829,0.00487339,0.001259224,0.002809734,0.105388,0.2939128,0.5788587],"study_design_scores_gemma":[0.00003141835,0.00004269649,0.0008715363,0.002617604,0.00003402918,0.0003572656,0.001155599,0.00008927655,0.0002904726,0.007172814,0.9873019,0.00003529638],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00198609,0.6621487,0.002492036,0.3017982,0.004747471,0.00007360902,0.0001609438,0.00006934725,0.02652353],"genre_scores_gemma":[0.03279493,0.8810926,0.006976669,0.0698892,0.003355652,0.00007622987,0.0002454788,0.00006369044,0.005505433],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5739254,"threshold_uncertainty_score":0.8571676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01834946478316436,"score_gpt":0.312699512954759,"score_spread":0.2943500481715947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}