{"id":"W4403630814","doi":"10.1101/2024.10.18.619157","title":"Exploring the Relationship Between Extracellular Vesicles, the Dendritic Cell Immunoreceptor and MicroRNA-155 in an In Vivo Model of HIV-1 Infection to Understand the Disease and Develop New Treatments","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Extracellular vesicles; microRNA; In vivo; Microvesicles; Disease; Extracellular; Cell biology; Cell; Biology; Dendritic cell; Human immunodeficiency virus (HIV); Extracellular vesicle; Immunology; Immune system; Medicine; Gene; Genetics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004226515,0.0004865653,0.0004359662,0.0004594047,0.0002271767,0.0004906064,0.0002911749,0.0008073509,0.001247688],"category_scores_gemma":[0.0001459138,0.0002681633,0.0003812979,0.0001645968,0.0003356438,0.0004688451,0.000228462,0.001708271,0.0004453332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004559659,"about_ca_system_score_gemma":0.0002238925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003810392,"about_ca_topic_score_gemma":0.0004362433,"domain_scores_codex":[0.9996344,0.00006764702,0.00003109821,0.00009743252,0.00008264937,0.0000867403],"domain_scores_gemma":[0.9998622,0.00002479197,0.00003097195,0.00001643536,0.0000189148,0.00004665763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003079903,0.0001783062,0.0001726873,0.00004206432,0.000006522505,0.00004626863,0.0000197093,0.00007543612,0.9980987,0.0001463451,0.00004754426,0.0008583653],"study_design_scores_gemma":[0.00005493361,0.002399836,0.003034907,0.00001289649,0.00003927962,0.0002895075,0.00008772365,0.004146733,0.9871206,0.0001587092,0.002643773,0.00001107913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839542,0.003539315,0.008583256,0.0002791116,0.0002306364,0.0001812784,0.0006641073,0.0001294262,0.002438621],"genre_scores_gemma":[0.9830564,0.001396382,0.009549354,0.0001891413,0.0000438536,0.0003607074,0.0006786874,0.00003875112,0.004686733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001247688,"threshold_uncertainty_score":0.004173875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05096735096022025,"score_gpt":0.2479363949898628,"score_spread":0.1969690440296425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}